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Found 32 with Last Name = 'bykowski' and Initial = 'd'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193054(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-indole-6-c...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193050(3-cyclopentyl-2-(furan-3-yl)-1-methyl-1H-indole-6-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193059(3-cyclopentyl-2-(furan-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162092(3-Cyclohexyl-1-methyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193060(3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193057(1-cyclohexyl-2-(furan-3-yl)-3-methyl-1H-indole-5-c...)
Affinity DataIC50:  44nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162094(3-Cyclohexyl-2-phenyl-1H-indole-6-carboxylic acid ...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193069(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-pyrrolo[2,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193063(3-cyclopentyl-2-(furan-3-yl)-7-hydroxy-1-methyl-1H...)
Affinity DataIC50:  75nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193055(3-cyclopentyl-2-(furan-3-yl)benzo[b]thiophene-6-ca...)
Affinity DataIC50:  78nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193052(3-cyclohexyl-1-methyl-2-phenyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  80nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193064(3-cyclopentyl-2-(furan-3-yl)benzofuran-6-carboxyli...)
Affinity DataIC50:  81nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193062(3-cyclohexyl-1-methyl-2-(pyridin-2-yl)-1H-indole-6...)
Affinity DataIC50:  90nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50370756(CHEMBL1789968)
Affinity DataIC50:  150nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193053(1-cyclohexyl-3-methyl-2-phenyl-1H-indole-5-carboxy...)
Affinity DataIC50:  180nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193067(3-cyclohexyl-2-(pyridin-2-yl)-1H-indole-6-carboxyl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193051(7-chloro-3-cyclopentyl-2-(furan-3-yl)-1-methyl-1H-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193066(3-cyclopentyl-2-(furan-3-yl)-7-methoxy-1-methyl-1H...)
Affinity DataIC50:  340nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193058(3-cyclopentyl-2-(furan-3-yl)-7-(methoxycarbonyl)-1...)
Affinity DataIC50:  480nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193049(1-cyclohexyl-3-methyl-2-(pyridin-2-yl)-1H-indole-5...)
Affinity DataIC50:  820nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193071(1-cyclopentyl-2-(furan-3-yl)-1H-benzo[d]imidazole-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137480(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137479(1-Cyclohexyl-2-phenyl-1H-benzoimidazole-5-carboxyl...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193068(3-cyclopentyl-2-(furan-3-yl)-1-methyl-1H-indole-6,...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193061(3-(4-cyclohexyl-5-(pyridin-2-yl)-1H-pyrrol-2-yl)ac...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193065(3-(1-cyclohexyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193070(3-cyclopentyl-2-furan-3-yl-1,1-dioxo-1H-1lambda*6*...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193054(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-indole-6-c...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of calf thymus DNA dependent RNA polymerase 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193054(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-indole-6-c...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of poliovirus RNA dependent RNA polymeraseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase II subunit RPB1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193060(3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of calf thymus DNA dependent RNA polymerase 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193060(3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...)
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of poliovirus RNA dependent RNA polymeraseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed