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Found 534 with Last Name = 'campbell' and Initial = 'uc'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334773(CHEMBL1642904 | trans-((2R,4S)-4-(3,4-dichlorophen...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337830(CHEMBL1683875 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(CHEMBL1642912 | Cis-2-((2S,4S)-4-(3,4-dichlorophen...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337822(4-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)morpho...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334787(CHEMBL1642902 | cis-((2S,4S)-4-(3,4-dichlorophenyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(CHEMBL1683873 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337833(CHEMBL1683902 | N,N-dimethyl-1-(1-(naphthalen-2-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337833(CHEMBL1683902 | N,N-dimethyl-1-(1-(naphthalen-2-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50028094((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334770(CHEMBL1642900 | cis-(2S,4S)-4-(3,4-dichlorophenyl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334916(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337834(CHEMBL1683872 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334764(CHEMBL1642894 | trans-(2R,4S)-4-(3,4-dichloropheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337818(CHEMBL1683876 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337833(CHEMBL1683902 | N,N-dimethyl-1-(1-(naphthalen-2-yl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334768(CHEMBL1642898 | trans-(2R,4S)-4-(3,4-dichloropheny...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334783(CHEMBL1642914 | trans-(1S,2S)-1-(3,4-dichloropheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334766(CHEMBL1642896 | cis-(2S,4S)-4-(3,4-dichlorophenyl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337830(CHEMBL1683875 | N-((1-(3,4-dichlorophenyl)cyclohex...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337835(1-(1-(3,4-dichlorophenyl)cyclopentyl)-N,N-dimethyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334775(CHEMBL1642906 | trans-1-((2R,4S)-4-(3,4-dichloroph...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337916((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,3-dim...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]dopamine reuptake at human human recombinant DAT expressed in COS-7 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337827((1-(thiophen-2-yl)cyclohexyl)methanamine | CHEMBL1...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337836(1-(1-(3-chloro-4-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337827((1-(thiophen-2-yl)cyclohexyl)methanamine | CHEMBL1...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337836(1-(1-(3-chloro-4-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334787(CHEMBL1642902 | cis-((2S,4S)-4-(3,4-dichlorophenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337826(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)piperi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334778(CHEMBL1642909 | cis-1-((2R,4R)-4-(3,4-dichlorophen...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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