Compile Data Set for Download or QSAR
maximum 50k data
Found 2041 with Last Name = 'cavalli' and Initial = 'a'
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.000340nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine O-acetyltransferase(RAT)
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.224nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(CHEMBL15056 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238406(CHEMBL4082584)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50268107(CHEMBL485862 | CHEMBL500634 | N-(2-(2-phenyl-6-(4-...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.407nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.427nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.427nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.513nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.513nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.589nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50472355(CHEMBL135974)
Affinity DataKi:  0.832nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  0.933nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413803(CHEMBL487754)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM120262(EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...)
Affinity DataKi:  1.60nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238381(CHEMBL4064795)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365309(CHEMBL1955915)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50472358(CHEMBL132378)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365316(CHEMBL1955922)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365310(CHEMBL1955916)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365322(CHEMBL1955899)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238384(CHEMBL4059885)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50229885(CHEMBL260331 | CHEMBL506685 | N-(benzo[d][1,3]diox...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50229885(CHEMBL260331 | CHEMBL506685 | N-(benzo[d][1,3]diox...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50472353(CHEMBL135973)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365313(CHEMBL1955919)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50166984(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238404(CHEMBL4097391)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238388(CHEMBL4079360)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50474375(CHEMBL145785)
Affinity DataKi:  7.40nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238380(CHEMBL4079325)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365317(CHEMBL1955923)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50472353(CHEMBL135973)
Affinity DataKi:  7.90nMAssay Description:Ability to displace [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238393(CHEMBL4089735)
Affinity DataKi:  8.10nMAssay Description:The binding affinity was evaluated against [3H]dalamid binding to neuroblastoma X glioma hybrid cell NG108-15 (Opioid receptor delta 1)membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365325(CHEMBL1955902)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50236738(3-ethyl-1-propyl-8-(1-(3-(trifluoromethyl)benzyl)-...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [125I]-ABOPX from human recombinant adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50474380(CHEMBL143026)
Affinity DataKi:  8.90nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238389(CHEMBL4066559)
Affinity DataKi:  8.90nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365301(CHEMBL1955907)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50365311(CHEMBL1955917)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2041 total ) | Next | Last >>
Jump to: