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Found 27 with Last Name = 'chadwick' and Initial = 'j'
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50311847(2-(3-(2-(2-hydroxy-5-nitrobenzoyl)hydrazono)-2-oxo...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant BACE1 at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50311848(CHEMBL1080086 | N-cyclohexyl-2-(3-(2-(2-hydroxy-5-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant BACE1 at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427058(CHEMBL2322538)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427058(CHEMBL2322538)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427056(CHEMBL2322539)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427057(CHEMBL2322537)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427053(CHEMBL2322541)
Affinity DataIC50:  5.89E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427045(CHEMBL2322830)
Affinity DataIC50:  6.33E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427056(CHEMBL2322539)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50:  7.71E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50:  8.57E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427051(CHEMBL2322534)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427048(CHEMBL2322831)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427047(CHEMBL2322832)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427049(CHEMBL2322829)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427052(CHEMBL2322533)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427050(CHEMBL2322542)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427057(CHEMBL2322537)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427054(CHEMBL2322540)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50:  2.07E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427054(CHEMBL2322540)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427053(CHEMBL2322541)
Affinity DataIC50:  3.19E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427046(CHEMBL2322833)
Affinity DataIC50:  3.23E+5nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427045(CHEMBL2322830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50427046(CHEMBL2322833)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed