Affinity DataKi: 0.380nMAssay Description:Competitive inhibition of human Aurora B ATP binding site by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human Aurora C ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Competitive inhibition of Aurora C ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
Affinity DataKi: 66nMpH: 6.8Assay Description:wild-type HCT116 selected at 6WT-6x the IC95More data for this Ligand-Target Pair
Affinity DataKi: 109nMpH: 6.8Assay Description:wild-type HCT116 selected at 3 the IC95More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Competitive inhibition of human Aurora A ATP binding siteMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair