Compile Data Set for Download or QSAR
maximum 50k data
Found 72 with Last Name = 'chou' and Initial = 'cc'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123438((3,5-Dichloro-pyridin-4-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  0.700nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50104946((2,4-Dimethyl-pyridin-3-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  2nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123436((3,5-Dichloro-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  2.70nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123435((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataKi:  3nMAssay Description:Ability of compound to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123445((3,5-Dimethyl-pyridin-4-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  5.20nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50104956((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  7nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123444((4,6-Dimethyl-2-trifluoromethyl-pyrimidin-5-yl)-(4...)
Affinity DataKi:  10nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123442((4-Methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromet...)
Affinity DataKi:  10nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123443((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-...)
Affinity DataKi:  11nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123437((2-Methoxy-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-...)
Affinity DataKi:  11nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123446((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataKi:  11nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123439((4,6-Dimethyl-2-phenyl-pyrimidin-5-yl)-(4-methyl-4...)
Affinity DataKi:  12nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123447((3,5-Dimethyl-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  18nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123440(4-((S)-1-{(S)-4-[1-(4,6-Dimethyl-pyrimidine-5-carb...)
Affinity DataKi:  20nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123441((2-Amino-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-4-...)
Affinity DataKi:  38nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123446((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataKi:  68nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123440(4-((S)-1-{(S)-4-[1-(4,6-Dimethyl-pyrimidine-5-carb...)
Affinity DataKi:  164nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123443((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-...)
Affinity DataKi:  169nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123437((2-Methoxy-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-...)
Affinity DataKi:  202nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50104956((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123447((3,5-Dimethyl-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  255nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123436((3,5-Dichloro-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  348nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50104956((2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-methyl-4-{(S)...)
Affinity DataKi:  350nMAssay Description:Binding affinity of the compound towards muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123435((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataKi:  456nMAssay Description:Inhibition of binding affinity of the compound to muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123435((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataKi:  575nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123444((4,6-Dimethyl-2-trifluoromethyl-pyrimidin-5-yl)-(4...)
Affinity DataKi:  613nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123442((4-Methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromet...)
Affinity DataKi:  985nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123441((2-Amino-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-4-...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123439((4,6-Dimethyl-2-phenyl-pyrimidin-5-yl)-(4-methyl-4...)
Affinity DataKi:  1.23E+3nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123445((3,5-Dimethyl-pyridin-4-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  1.68E+3nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123438((3,5-Dichloro-pyridin-4-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50104946((2,4-Dimethyl-pyridin-3-yl)-(4-methyl-4-{(S)-3-met...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity towards muscarinic receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50123435((4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-m...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of 0.1 nM of MIP-1beta induced migration of recombinant mouse pro-B cell line BA/F3 expressing human CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50353484(CHEMBL1830587)
Affinity DataIC50:  600nMAssay Description:Inhibition of human ILK activity assessed myelin basic protein phosphorylation by radiometric kinase assay in the presence of [gamma 32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of 50% of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153764((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50153762(3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078218(CHEMBL3414677)
Affinity DataKd:  450nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078219(CHEMBL3414676)
Affinity DataKd:  280nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078220(CHEMBL3414675)
Affinity DataKd:  320nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078221(CHEMBL3414674)
Affinity DataKd:  410nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078222(CHEMBL3414673)
Affinity DataKd:  350nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078223(CHEMBL3414672)
Affinity DataKd:  410nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078256(CHEMBL3414671)
Affinity DataKd:  8.50E+3nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: