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Found 894 with Last Name = 'colussi' and Initial = 'd'
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080514(3-[(R)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  0.0470nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50114534((2R,3R)-3-[(3'-Aminomethyl-biphenyl-4-carbonyl)-am...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50114539((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyr...)
Affinity DataKi:  0.400nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085393((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[(3'-carbamoy...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085393((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[(3'-carbamoy...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114544((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-(4-pyridin-4-...)
Affinity DataKi:  0.5nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114543((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyr...)
Affinity DataKi:  0.580nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14059(4-hydroxy-3-[[(3S)-2-oxo-3-(9-thia-5-azabicyclo[4....)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114536((2R,3R)-3-[(3'-Aminomethyl-biphenyl-4-carbonyl)-am...)
Affinity DataKi:  0.700nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi:  0.75nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114540(3-{4-[(1R,2R)-3-(3-Carbamimidoyl-phenyl)-2-methoxy...)
Affinity DataKi:  0.800nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114537((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-(4-pyridin-2-...)
Affinity DataKi:  0.890nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM12597(CHEMBL48046 | RPR128515 | methyl (2R,3R)-2-{3-[ami...)
Affinity DataKi:  0.900nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM12594(4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXO...)
Affinity DataKi:  1nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50111966(1-(4-Amino-quinazolin-7-ylmethyl)-4-(6-chloro-benz...)
Affinity DataKi:  1nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114531((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[(3'-dimethyl...)
Affinity DataKi:  1nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114548(2-{4-[(1R,2R)-3-(3-Carbamimidoyl-phenyl)-2-methoxy...)
Affinity DataKi:  1.20nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM12594(4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXO...)
Affinity DataKi:  1.30nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081505(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114547((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyr...)
Affinity DataKi:  2nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081499(4-Hydroxy-3-[(S)-2-oxo-3-(thieno[2,3-c]pyridine-2-...)
Affinity DataKi:  2nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13304(4-hydroxy-3-[((3S)-2-oxo-3-{[(5-pyridin-3-ylthien-...)
Affinity DataKi:  2nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50085405(2'-Sulfamoyl-biphenyl-4-carboxylic acid [3-(5-carb...)
Affinity DataKi:  2nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081512(3-[(S)-3-(4-Chloro-thieno[3,2-c]pyridine-2-sulfony...)
Affinity DataKi:  2nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114528((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[(4'-carbamoy...)
Affinity DataKi:  2nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114542(4-{4-[(1R,2R)-3-(3-Carbamimidoyl-phenyl)-2-methoxy...)
Affinity DataKi:  2.70nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13286(4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfon...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13286(4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfon...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50111958(1-(4-Amino-quinazolin-7-ylmethyl)-4-(6-chloro-1H-b...)
Affinity DataKi:  3nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114538((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1H-imidaz...)
Affinity DataKi:  3nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13306(4-Hydroxy-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-yls...)
Affinity DataKi:  3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081510(4-Amino-3-[(S)-3-(5-chloro-thieno[3,2-b]pyridine-2...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081517(4-Hydroxy-3-[(S)-2-oxo-3-(thieno[3,2-c]pyridine-2-...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13283(4-amino-3-({(3S)-3-[[(7-methoxy-2-naphthyl)sulfony...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114530((2R,3R)-3-[(3'-Aminomethyl-biphenyl-4-carbonyl)-am...)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081506(3-[(S)-3-(7-Chloro-thieno[2,3-c]pyridine-2-sulfony...)
Affinity DataKi:  5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085406((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085390(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[(E)-3...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085406((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  5.30nMAssay Description:In vitro inhibitory activity against human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085406((2R,3R)-3-[(Biphenyl-4-carbonyl)-amino]-2-(3-carba...)
Affinity DataKi:  5.30nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50114541((2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-(4-imidazol-1...)
Affinity DataKi:  6nMAssay Description:Inibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081009(CHEMBL85938 | Thieno[3,2-b]pyridine-2-sulfonic aci...)
Affinity DataKi:  6nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13281(4-Amino-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonyl...)
Affinity DataKi:  6nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13281(4-Amino-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonyl...)
Affinity DataKi:  6nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13303(4-Amino-3-[2-oxo-3-(S)-(5-pyridin-3-ylthiophene-2-...)
Affinity DataKi:  6nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13279(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  6.90nM ΔG°:  -46.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13279(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  7nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi:  7nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM13305(4-Amino-3-[3-(S)-(5-isoxazol-3-ylthiophene-2-ylsul...)
Affinity DataKi:  7nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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