Affinity DataKi: 21nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Compound was evaluated for time-dependent inactivation of Ribonucleotide diphosphate reductase (RDPR) in E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 374nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 505nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 261nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 368nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 976nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 7.98E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: 1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: 1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair