Compile Data Set for Download or QSAR
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Found 54 with Last Name = 'd''andrea' and Initial = 'sv'
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007002(3,4-Dichloro-N-(3-dimethylamino-1,2,3,4-tetrahydro...)
Affinity DataKi:  21nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50229403(CHEMBL2311130)
Affinity DataKi:  52nMAssay Description:Compound was evaluated for time-dependent inactivation of Ribonucleotide diphosphate reductase (RDPR) in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006996(3,4-Dichloro-N-methyl-N-(3-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataKi:  374nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007004(3,4-Dichloro-N-(2-dimethylamino-1,2,3,4-tetrahydro...)
Affinity DataKi:  505nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007001(3,4-Dichloro-N-methyl-N-(3-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006994(2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-pyrrolidin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007000(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006999(2-(3,4-Dichloro-phenyl)-N-(2-dimethylamino-1,2,3,4...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006998(2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-pyrrolidin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006997(3,4-Dichloro-N-methyl-N-(2-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287622(CHEMBL4160876)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287595(CHEMBL3921126)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006994(2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-pyrrolidin-1...)
Affinity DataIC50:  5.20nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  5.40nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287648(CHEMBL3895075)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007000(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataIC50:  7.30nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006999(2-(3,4-Dichloro-phenyl)-N-(2-dimethylamino-1,2,3,4...)
Affinity DataIC50:  12nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287621(CHEMBL4171493)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287586(CHEMBL4176000)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287588(CHEMBL4177477)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287685(CHEMBL4168149)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006996(3,4-Dichloro-N-methyl-N-(3-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataIC50:  29nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287587(CHEMBL4159744)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007002(3,4-Dichloro-N-(3-dimethylamino-1,2,3,4-tetrahydro...)
Affinity DataIC50:  56nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007001(3,4-Dichloro-N-methyl-N-(3-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataIC50:  85nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006998(2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-pyrrolidin-1...)
Affinity DataIC50:  145nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287686(CHEMBL4161286)
Affinity DataIC50:  261nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50006997(3,4-Dichloro-N-methyl-N-(2-pyrrolidin-1-yl-1,2,3,4...)
Affinity DataIC50:  368nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287593(CHEMBL4160158)
Affinity DataIC50:  976nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287592(CHEMBL4169219)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291391(3-[(E)-1-((E)-2-Carboxy-1-methyl-vinyl)-4-(5,5,8,8...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287651(CHEMBL4170379)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50007004(3,4-Dichloro-N-(2-dimethylamino-1,2,3,4-tetrahydro...)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287641(CHEMBL4168077)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287638(CHEMBL4172603)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291389(3-{(E)-3-Carbamoyl-2-methyl-1-[1-(5,5,8,8-tetramet...)
Affinity DataIC50:  4.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291390(3-{(E)-3-Carboxy-1-[1-(4-decyloxy-phenyl)-meth-(E)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287627(CHEMBL4164707)
Affinity DataIC50:  7.98E+3nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291388(3-[(E)-4-(4-Adamantan-1-yl-3-hydroxy-phenyl)-1-((E...)
Affinity DataIC50:  8.00E+3nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291387(3-{(E)-3-Carboxy-1-[1-(6-decyloxy-naphthalen-2-yl)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291392(3-{(E)-3-Carboxy-2-methyl-1-[1-(5,5,8,8-tetramethy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291386(3-{(E)-3-Carboxy-2-methyl-1-[1-[6-(3-phenyl-propox...)
Affinity DataIC50:  1.70E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA polymerase beta(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50287647(CHEMBL4174861)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288286(3-[(1E,3E,5E)-1-((E)-2-Carboxy-1-methyl-vinyl)-4-m...)
Affinity DataIC50:  4.00E+4nMAssay Description:Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataEC50:  1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50268398(CHEMBL4061940)
Affinity DataEC50:  1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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