Compile Data Set for Download or QSAR
maximum 50k data
Found 111 with Last Name = 'darrow' and Initial = 'jw'
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of VEGFR2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  13nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  26nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  33nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  35nMAssay Description:Inhibition of EPHA2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312184(1-(2-hydroxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  49nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072425(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataIC50:  50nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50181434((S)-2-{3-[3-(4-Benzoylphenyl)ureido]-2,4-dioxo-5-p...)
Affinity DataIC50:  61nMAssay Description:Displacement of [125I-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat CCK receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  62nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312187(1-(2-chloro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  66nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312200(1-(3-(8-(methyl(pyridin-4-ylmethyl)amino)imidazo[1...)
Affinity DataIC50:  69nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312153(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of VEGFR3 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  75nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312178(1-(5-chloro-2-methoxyphenyl)-3-(3-(8-(pyridin-4-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312175(1-(2-methoxy-5-methylphenyl)-3-(3-(8-(pyridin-4-yl...)
Affinity DataIC50:  78nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072421(2-{3-[3-(3-Benzoyl-phenyl)-ureido]-2,4-dioxo-5-phe...)
Affinity DataIC50:  80nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312155(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312185(1-(2,5-dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethyl...)
Affinity DataIC50:  101nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312201(1-(3-(8-(pyridin-4-ylmethoxy)imidazo[1,2-a]pyrazin...)
Affinity DataIC50:  105nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312174(1-(5-cyano-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  125nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312177(1-(5-chloro-2-phenoxyphenyl)-3-(3-(8-(pyridin-4-yl...)
Affinity DataIC50:  138nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312203(1-(3-(8-(2-(pyridin-4-yl)ethylamino)imidazo[1,2-a]...)
Affinity DataIC50:  158nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312176(1-(5-chloro-2-methylphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  160nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072422(2-{3-[3-(3-Benzoyl-phenyl)-ureido]-2,4-dioxo-5-phe...)
Affinity DataIC50:  160nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312197(1-(3-chlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamin...)
Affinity DataIC50:  165nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312169(1-(5-bromo-2,4-dimethoxyphenyl)-3-(3-(8-(pyridin-4...)
Affinity DataIC50:  206nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312167(1-(2,4-diethoxy-5-(trifluoromethyl)phenyl)-3-(3-(8...)
Affinity DataIC50:  211nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312196(1-(3-bromophenyl)-3-(3-(8-(pyridin-4-ylmethylamino...)
Affinity DataIC50:  213nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072427(1-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl)-2,4-d...)
Affinity DataIC50:  250nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072420(2-{3-[3-(3-Benzoyl-phenyl)-ureido]-2,4-dioxo-5-phe...)
Affinity DataIC50:  290nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312195(1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072424(2-(2,4-Dioxo-5-phenyl-3-{3-[3-(3-trifluoromethyl-3...)
Affinity DataIC50:  310nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072428(2-{3-[3-(3-Benzoyl-phenyl)-ureido]-2,4-dioxo-5-phe...)
Affinity DataIC50:  350nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50072419(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataIC50:  390nMAssay Description:Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50:  400nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312170(1-(5-chloro-2,4-dimethoxyphenyl)-3-(3-(8-(pyridin-...)
Affinity DataIC50:  402nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 111 total ) | Next | Last >>
Jump to: