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Found 22 with Last Name = 'daval' and Initial = 'sb'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.0955nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.170nMAssay Description:Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50122054(8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]dia...)
Affinity DataKi:  60.3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataKi:  891nMAssay Description:Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401040(CHEMBL2206333)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401038(CHEMBL2206335)
Affinity DataKi:  1.29E+3nMAssay Description:Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401038(CHEMBL2206335)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50149891(2,2',2''-[1,2,3-BENZENE-TRIYLTRIS(OXY)]TRIS[N,N,N-...)
Affinity DataKi:  8.51E+3nMAssay Description:Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401037(BRUCINE)
Affinity DataKi:  4.47E+4nMAssay Description:Competitive inhibition of EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 4 hrs by FRET assay in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM54993(4-[6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401040(CHEMBL2206333)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as inhibition of carbachol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401038(CHEMBL2206335)
Affinity DataIC50:  3.70E+3nMAssay Description:Antagonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as inhibition of carbachol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataEC50:  740nMAssay Description:Partial agonist activity at human full length M1 receptor expressed in HEK293 cells assessed as induction of calcium response by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as induction of calcium respo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50149891(2,2',2''-[1,2,3-BENZENE-TRIYLTRIS(OXY)]TRIS[N,N,N-...)
Affinity DataEC50:  1.74E+5nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as reduction of [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50401040(CHEMBL2206333)
Affinity DataEC50:  2.51E+4nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as reduction of [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50149891(2,2',2''-[1,2,3-BENZENE-TRIYLTRIS(OXY)]TRIS[N,N,N-...)
Affinity DataEC50:  1.70E+5nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as reduction of [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataEC50:  450nMAssay Description:Partial agonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as induction of calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataEC50:  720nMAssay Description:Partial agonist activity at EGFP-fused human M1 receptor N-terminal truncated at 11 residues expressed in HEK293 cells assessed as induction of calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)
Affinity DataEC50:  210nMAssay Description:Partial agonist activity at EGFP-fused human full length M1 receptor expressed in HEK293 cells assessed as induction of calcium response by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at human M3 receptor in HEK293 cells assessed as induction of calcium response by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed