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Found 266 with Last Name = 'dickson' and Initial = 'jm'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245691(9-hydroxy-6-(3-(methylamino)propyl)-4-phenylpyrrol...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537407(CHEMBL4563749)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537375(CHEMBL4547407)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537386(CHEMBL4529406)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245342(4-(2-Chlorophenyl)-9-hydroxy-6-[2-hydroxy-3-(methy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537376(CHEMBL4569104)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537404(CHEMBL4561973)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245693(4-(2,6-dichlorophenyl)-9-hydroxy-6-(3-(methylamino...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537405(CHEMBL4564359)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537397(CHEMBL4587949)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537408(CHEMBL4590814)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537385(CHEMBL4538078)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537402(CHEMBL4589962)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537393(CHEMBL4524276)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245523(3-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537410(CHEMBL4535132)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537381(CHEMBL4589994)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245496(4-(2,6-Dichlorophenyl)-9-hydroxy-6-(3-hydroxypropy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245387(3-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537388(CHEMBL4559189)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537384(CHEMBL4533703)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537396(CHEMBL4556404)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537403(CHEMBL4546341)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537383(CHEMBL4519688)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245457(4-(2,6-Dichlorophenyl)-9-hydroxy-6-(2-hydroxyethyl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537395(CHEMBL4520157)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245425(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-1,2,4-triazo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245384(3-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50232241(4-(2-Chlorophenyl)-9-hydroxy-6-(3-hydroxypropyl)-p...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537406(CHEMBL4522126)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50192371(4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537378(CHEMBL4583306)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human N-terminal p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245386(3-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537377(CHEMBL4520574)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245692(4-(2-chlorophenyl)-9-hydroxy-6-(3-(methylamino)pro...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245458(4-(4-(2-Chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537387(CHEMBL4591768)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537380(CHEMBL4533732)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537379(CHEMBL4528477)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245341(3-(4-(2,6-dichlorophenyl)-9-hydroxy-1,3-dioxo-2,3-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245525(3-(4-(2-chlorophenyl)-9-hydroxy-1,3-dioxo-2,3-dihy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537394(CHEMBL4528549)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245497(9-Hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537391(CHEMBL4589172)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human N-terminal p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245426(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-1,2,4-triazo...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50537389(CHEMBL4567154)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human N-terminal p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50537389(CHEMBL4567154)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human N-terminal p110alpha/p85alpha expressed in baculovirus infected Sf9 insect cells using PIP2 as substrate by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245731(6-[3-(Dimethylamino)propyl]-9-hydroxy-4-phenylpyrr...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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