BindingDB PrimarySearch

Found 502 with Last Name = 'ellard' and Initial = 'k'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387544(CHEMBL2057373)

IC50: 2.51nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387541(CHEMBL2057368)

IC50: 2.51nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387546(CHEMBL2057363)

IC50: 3.16nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387543(CHEMBL2057372)

IC50: 3.98nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387539(CHEMBL2057366)

IC50: 6.31nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389412(CHEMBL2064508)

IC50: 6.31nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387541(CHEMBL2057368)

IC50: 6.31nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387542(CHEMBL2057371)

IC50: 6.31nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401144(CHEMBL2205771)

IC50: 7.90nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387538(CHEMBL2057365)

IC50: 7.94nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389431(CHEMBL2064501)

IC50: 7.94nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389427(CHEMBL2064507)

IC50: 7.94nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387540(CHEMBL2057367)

IC50: 10nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387530(CHEMBL2059910)

IC50: 12.6nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387544(CHEMBL2057373)

IC50: 12.6nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387536(CHEMBL2057362)

IC50: 12.6nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401152(CHEMBL2205766)

IC50: 13nMAssay Description:Inhibition of CK2a1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Target of rapamycin complex subunit LST8(Homo sapiens)
Cellzome

Curated by ChEMBL

BDBM50535043(CHEMBL4577549)

IC50: 15nMAssay Description:Inhibition of mTORC1 in HEK293T/17 cells assessed as reduction in S6RP phosphorylation at Ser-240/244 residue after 2 hrs by sandwich immunoassayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

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Target of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
Cellzome

Curated by ChEMBL

BDBM50535043(CHEMBL4577549)

IC50: 15nMAssay Description:Inhibition of mTORC2 in HEK293T/17 cells assessed as reduction in Akt phosphorylation at Ser-473 residue after 2 hrs by sandwich immunoassayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387527(CHEMBL2057370)

IC50: 15.8nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387548(CHEMBL2059913)

IC50: 15.8nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387543(CHEMBL2057372)

IC50: 15.8nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387538(CHEMBL2057365)

IC50: 15.8nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389391(CHEMBL2064512)

IC50: 15.8nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401150(CHEMBL2205763)

IC50: 16nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387548(CHEMBL2059913)

IC50: 19.9nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401153(CHEMBL2205767)

IC50: 20nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401147(CHEMBL2205768)

IC50: 20nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401149(CHEMBL2205773)

IC50: 20nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401143(CHEMBL2205774)

IC50: 25nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401152(CHEMBL2205766)

IC50: 25nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401148(CHEMBL2205765)

IC50: 25nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401146(CHEMBL2205772)

IC50: 25nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389420(CHEMBL2064571)

IC50: 25nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387535(CHEMBL2057361)

IC50: 25.1nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387529(CHEMBL2059909)

IC50: 25.1nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389420(CHEMBL2064571)

IC50: 25.1nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387529(CHEMBL2059909)

IC50: 25.1nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387539(CHEMBL2057366)

IC50: 25.1nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387537(CHEMBL2057364)

IC50: 25.1nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387536(CHEMBL2057362)

IC50: 25.1nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389428(CHEMBL2064511)

IC50: 31.6nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387535(CHEMBL2057361)

IC50: 31.6nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401151(CHEMBL2205764)

IC50: 32nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389408(CHEMBL2064500)

IC50: 39.8nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389395(CHEMBL2064482)

IC50: 39.8nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401142(CHEMBL2205769)

IC50: 40nMAssay Description:Inhibition of PIK3CgMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387547(CHEMBL2057369)

IC50: 50.1nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50387547(CHEMBL2057369)

IC50: 63.1nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50389407(CHEMBL2064499)

IC50: 63.1nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Displayed 1 to 50 (of 502 total ) | Next | Last >>

Filter my 502 hits

Targets 160▿
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 105
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 85
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 85
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 45
- Neuropilin-1 18
- Serine/threonine-protein kinase mTOR 6
- Mitogen-activated protein kinase 14 2
- Casein kinase II subunit alpha 2
- Casein kinase II subunit alpha' 2
- Mitogen-activated protein kinase 8 2
- Cyclin-G-associated kinase 1
- Tyrosine-protein kinase Tec 1
- Tyrosine-protein kinase JAK1 1
- BMP-2-inducible protein kinase 1
- Tyrosine-protein kinase FRK 1
- LIM domain kinase 1 1
- LIM domain kinase 2 1
- Hepatocyte growth factor receptor 1
- Non-receptor tyrosine-protein kinase TYK2 1
- Serine/threonine-protein kinase B-raf 1
- Serine/threonine-protein kinase Nek9 1
- Glycogen synthase kinase-3 alpha 1
- Glycogen synthase kinase-3 beta 1
- Serine-protein kinase ATM 1
- AP2-associated protein kinase 1 1
- Serine/threonine-protein kinase Nek2 1
- Macrophage-stimulating protein receptor 1
- Serine/threonine-protein kinase SIK3 [59-1321] 1
- Protein kinase C theta type 1
- Dual specificity mitogen-activated protein kinase kinase 2 1
- Serine/threonine-protein kinase PAK 4 1
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Tyrosine-protein kinase JAK2 1
- MAP/microtubule affinity-regulating kinase 4 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- Dual specificity mitogen-activated protein kinase kinase 5 1
- Casein kinase I isoform gamma-3 1
- Casein kinase I isoform epsilon 1
- Casein kinase I isoform gamma-1 1
- Ephrin type-A receptor 3 1
- Ephrin type-A receptor 2 1
- Tyrosine-protein kinase BTK 1
- Eukaryotic translation initiation factor 2-alpha kinase 1 1
- Tyrosine-protein kinase ITK/TSK 1
- Bone morphogenetic protein receptor type-1A 1
- Activin receptor type-1 1
- Tyrosine-protein kinase Blk 1
- Receptor-interacting serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase 16 1
- Epidermal growth factor receptor 1
- Non-receptor tyrosine-protein kinase TNK1 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Phosphoinositide 3-kinase regulatory subunit 4 1
- Receptor-interacting serine/threonine-protein kinase 3 1
- Serine/threonine-protein kinase NLK 1
- Target of rapamycin complex subunit LST8 1
- Integrin-linked protein kinase 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3 1
- Wee1-like protein kinase 1
- Casein kinase I isoform delta 1
- Protein kinase C beta type 1
- Tyrosine-protein kinase Lyn 1
- Dual specificity testis-specific protein kinase 2 1
- Focal adhesion kinase 1 1
- Dual specificity testis-specific protein kinase 1 1
- Cyclin-dependent kinase 2 1
- Cyclin-dependent kinase 1 1
- Ephrin type-B receptor 4 1
- Ephrin type-B receptor 2 1
- Activated CDC42 kinase 1 1
- Ephrin type-B receptor 6 1
- MAP kinase-activated protein kinase 3 1
- Target of rapamycin complex 2 subunit MAPKAP1 1
- Epithelial discoidin domain-containing receptor 1 1
- Phosphatidylinositol 4-kinase beta 1
- Tyrosine-protein kinase Fer 1
- Serine/threonine-protein kinase D2 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 1
- Calcium/calmodulin-dependent protein kinase type II subunit delta 1
- Cyclin-dependent kinase 9 1
- Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1
- Cyclin-dependent kinase 7 1
- Serine/threonine-protein kinase TAO1 1
- Cyclin-dependent kinase 6 1
- Cyclin-dependent kinase 5 1
- Calcium/calmodulin-dependent protein kinase kinase 1 1
- Serine/threonine-protein kinase TAO3 1
- Calcium/calmodulin-dependent protein kinase kinase 2 1
- Serine/threonine-protein kinase TAO2 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Mitogen-activated protein kinase kinase kinase kinase 3 1
- Mitogen-activated protein kinase kinase kinase kinase 1 1
- Protein-tyrosine kinase 6 1
- Mitogen-activated protein kinase kinase kinase kinase 5 1
- Serine/threonine-protein kinase ATR 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 1
- Activin receptor type-1B 1
- Bromodomain-containing protein 4 1
- Bromodomain-containing protein 3 1
- Mitogen-activated protein kinase kinase kinase 5 1
- Interleukin-1 receptor-associated kinase 1 1
- Bromodomain-containing protein 2 1
- Tyrosine-protein kinase ABL2 1
- Tyrosine-protein kinase ABL1 1
- Interleukin-1 receptor-associated kinase 3 1
- Mitogen-activated protein kinase kinase kinase 2 1
- Atypical kinase COQ8B, mitochondrial 1
- Serine/threonine-protein kinase A-Raf 1
- Mitogen-activated protein kinase kinase kinase 1 1
- Mitogen-activated protein kinase kinase kinase 4 1
- Mitogen-activated protein kinase kinase kinase 3 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Activin receptor type-2B 1
- Tyrosine-protein kinase Fes/Fps 1
- Serine/threonine-protein kinase SIK2 1
- Activin receptor type-2A 1
- Serine/threonine-protein kinase ULK3 1
- Mitogen-activated protein kinase 1 1
- Serine/threonine-protein kinase 3 1
- 3-phosphoinositide-dependent protein kinase 1 1
- Tyrosine-protein kinase Lck 1
- Mitogen-activated protein kinase 3 1
- Serine/threonine-protein kinase 4 1
- Serine/threonine-protein kinase 17B 1
- Dual specificity protein kinase CLK1 1
- Protein kinase C delta type 1
- Dual specificity protein kinase CLK2 1
- Protein-tyrosine kinase 2-beta 1
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 1
- Potassium voltage-gated channel subfamily H member 2 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Serine/threonine-protein kinase N1 1
- Tyrosine-protein kinase SYK 1
- Ribosomal protein S6 kinase alpha-3 1
- Ribosomal protein S6 kinase alpha-1 1
- Serine/threonine-protein kinase TBK1 1
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 1
- Calcium/calmodulin-dependent protein kinase type 1D 1
- Serine/threonine-protein kinase RIO2 1
- Aurora kinase B 1
- Tyrosine-protein kinase Fgr 1
- Aurora kinase A 1
- Fibroblast growth factor receptor 1 1
- Mitogen-activated protein kinase kinase kinase 20 1
- Atypical kinase COQ8A, mitochondrial 1
- Serine/threonine-protein kinase PLK4 1
- Mitogen-activated protein kinase 11 1
- Casein kinase I isoform alpha 1
- Tyrosine-protein kinase Fyn 1
- Tyrosine-protein kinase CSK 1
- Protein kinase C alpha type 1
- eIF-2-alpha kinase GCN2 1
- Ribosomal protein S6 kinase alpha-4 1
- Ribosomal protein S6 kinase alpha-5 1
- Maternal embryonic leucine zipper kinase 1
- Phosphatidylinositol 4-kinase alpha 1
- Serine/threonine-protein kinase MARK2 1
- Tyrosine-protein kinase Yes 1
- Mitogen-activated protein kinase kinase kinase 11 1
- ...
Publications 5▿
- Bioorg Med Chem Lett 22: 4613-8 (2012) 216
- Bioorg Med Chem Lett 22: 5257-63 (2012) 173
- Bioorg Med Chem Lett 22: 4546-9 (2012) 87
- J Med Chem 53: 2215-26 (2010) 18
- ACS Med Chem Lett 7: 768-73 (2016) 8
Institutions 2▿
- Cellzome 484
- Domainex 18
Affinity: 2.5 to 6.3E+7 nM▿
- IC50 498
- Kd 4
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 3