Compile Data Set for Download or QSAR
maximum 50k data
Found 176 with Last Name = 'entzeroth' and Initial = 'm'
TargetHistone deacetylase 4(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of recombinant HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  82nMAssay Description:Inhibition of recombinant HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173482(4-(2-Oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piper...)
Affinity DataIC50:  0.0500nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  0.0600nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]-CGRP as radioligand after 180 minutes of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50:  2.70nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]-CGRP as radioligand after 180 minutes of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043257(6-Imidazo[1,2-a]pyridin-2-yl-4-methyl-2-propyl-1-[...)
Affinity DataIC50:  3nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043260(2-Butyl-6-(1,1-dioxo-1lambda*6*-[1,2]thiazinan-2-y...)
Affinity DataIC50:  3nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)
Affinity DataIC50:  3nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043244(4'-(1-Methyl-2'-propyl-1H-[2,5']bibenzoimidazolyl-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043277(1-{2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Affinity DataIC50:  4nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043246(4'-(6-Imidazo[1,2-a]pyridin-2-yl-4-methyl-2-propyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173472(4-(1-Phenyl-ureido)-piperidine-1-carboxylic acid [...)
Affinity DataIC50:  4.70nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043247(4-Methyl-2-propyl-6-pyridin-2-yl-1-[2'-(1H-tetrazo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043279(1-Methyl-2'-propyl-3'-[2'-(1H-tetrazol-5-yl)-biphe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50:  6.40nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]-CGRP as radioligand after 180 minutes of incubation at pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043248(3-{2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Affinity DataIC50:  8nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043263(1-{2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Affinity DataIC50:  10nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043255(2-Propyl-6-pyridin-2-yl-1-[2'-(1H-tetrazol-5-yl)-b...)
Affinity DataIC50:  11nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043271(1,7'-Dimethyl-2'-propyl-3'-[2'-(1H-tetrazol-5-yl)-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043252(1-{2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Affinity DataIC50:  21nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043269(4'-[2-Butyl-6-(3,3-dimethyl-ureido)-benzoimidazol-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043268(4'-[2-Butyl-6-(3-cyclohexyl-1-methyl-ureido)-benzo...)
Affinity DataIC50:  26nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50035429(4'-[2-Butyl-6-(3-cyclohexyl-ureido)-benzoimidazol-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50062162(CHEMBL264010 | FVPTDVGPFAF)
Affinity DataIC50:  29nMAssay Description:CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043281(4'-{2-Butyl-6-[methyl-(propane-1-sulfonyl)-amino]-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043249(4'-[2-Butyl-6-(1,1-dioxo-1lambda*6*-[1,2]thiazinan...)
Affinity DataIC50:  34nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  35nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248570(3-(1-(3-(dimethylamino)-2,2-dimethylpropyl)-2-phen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173486(4-(2-Oxo-benzooxazol-3-yl)-piperidine-1-carboxylic...)
Affinity DataIC50:  44nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248375(CHEMBL491688 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248475(3-(1-(2-(diethylamino)ethyl)-2-phenethyl-1H-benzo[...)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50:  56.7nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]-CGRP as radioligand after 180 minutes of incubation at pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248314(CHEMBL474746 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043270(4'-[2-Butyl-6-(2-oxo-piperidin-1-yl)-benzoimidazol...)
Affinity DataIC50:  81nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043265(4'-(2-Butyl-6-pentanoylamino-benzoimidazol-1-ylmet...)
Affinity DataIC50:  86nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248261(CHEMBL475145 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50030559(7S,8S-(betaMeF)2SP | CHEMBL2371143 | FVPTDVG-Tic-F...)
Affinity DataIC50:  146nMAssay Description:CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Dr. Karl Thomae

Curated by ChEMBL
LigandPNGBDBM50043275(4'-(6-Dimethylaminomethyl-4-methyl-2-propyl-benzoi...)
Affinity DataIC50:  158nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 176 total ) | Next | Last >>
Jump to: