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Found 81 with Last Name = 'eppley' and Initial = 'df'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078697(CHEMBL54138 | {(S)-7-[2-(1H-Imidazol-2-ylamino)-et...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059133(CHEMBL50106 | SB-223245 | {(S)-7-[(1H-Benzoimidazo...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078710(CHEMBL298782 | {(S)-7-[2-(6-Amino-pyridin-2-ylamin...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078696(CHEMBL52026 | {(S)-7-[(2-Amino-3H-imidazol-4-ylmet...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078703(CHEMBL301760 | {(S)-4-Methyl-3-oxo-7-[2-(pyridin-2...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078705(CHEMBL299591 | {(S)-7-[(6-Ethylamino-pyridin-2-ylm...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078698(CHEMBL296615 | {(S)-4-Methyl-7-[methyl-(6-methylam...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078706(CHEMBL52681 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078704(((S)-4-Methyl-7-{methyl-[2-(pyridin-2-ylamino)-eth...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078712(CHEMBL50028 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078711(CHEMBL50257 | {(S)-7-[2-(6-Amino-pyridin-2-yl)-eth...)
Affinity DataKi:  85nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078701(CHEMBL50510 | [(S)-7-(6-Amino-pyridin-2-ylcarbamoy...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078707(CHEMBL53987 | {(S)-4-Methyl-7-[2-(6-methyl-pyridin...)
Affinity DataKi:  280nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078709(CHEMBL53985 | {(S)-7-[(3H-Imidazol-4-ylmethyl)-car...)
Affinity DataKi:  490nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078696(CHEMBL52026 | {(S)-7-[(2-Amino-3H-imidazol-4-ylmet...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078700(CHEMBL417014 | [(S)-4-Methyl-3-oxo-7-(4-pyridin-2-...)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078707(CHEMBL53987 | {(S)-4-Methyl-7-[2-(6-methyl-pyridin...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078708(CHEMBL53725 | {(S)-4-Methyl-3-oxo-7-[2-(pyrimidin-...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078698(CHEMBL296615 | {(S)-4-Methyl-7-[methyl-(6-methylam...)
Affinity DataKi:  3.65E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078710(CHEMBL298782 | {(S)-7-[2-(6-Amino-pyridin-2-ylamin...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078702(CHEMBL300412 | {(S)-4-Methyl-3-oxo-7-[(pyridin-2-y...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078706(CHEMBL52681 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078697(CHEMBL54138 | {(S)-7-[2-(1H-Imidazol-2-ylamino)-et...)
Affinity DataKi:  8.20E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078711(CHEMBL50257 | {(S)-7-[2-(6-Amino-pyridin-2-yl)-eth...)
Affinity DataKi:  8.50E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078709(CHEMBL53985 | {(S)-7-[(3H-Imidazol-4-ylmethyl)-car...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078705(CHEMBL299591 | {(S)-7-[(6-Ethylamino-pyridin-2-ylm...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078704(((S)-4-Methyl-7-{methyl-[2-(pyridin-2-ylamino)-eth...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078699(CHEMBL50075 | [(S)-4-Methyl-3-oxo-7-(2-phenylamino...)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078703(CHEMBL301760 | {(S)-4-Methyl-3-oxo-7-[2-(pyridin-2...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059133(CHEMBL50106 | SB-223245 | {(S)-7-[(1H-Benzoimidazo...)
Affinity DataKi:  3.00E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078712(CHEMBL50028 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078700(CHEMBL417014 | [(S)-4-Methyl-3-oxo-7-(4-pyridin-2-...)
Affinity DataKi:  4.05E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078702(CHEMBL300412 | {(S)-4-Methyl-3-oxo-7-[(pyridin-2-y...)
Affinity DataKi:  4.15E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078699(CHEMBL50075 | [(S)-4-Methyl-3-oxo-7-(2-phenylamino...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078708(CHEMBL53725 | {(S)-4-Methyl-3-oxo-7-[2-(pyrimidin-...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078701(CHEMBL50510 | [(S)-7-(6-Amino-pyridin-2-ylcarbamoy...)
Affinity DataKi:  1.60E+5nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105938(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-ethoxy-5-oxo-1,5-...)
Affinity DataEC50:  600nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105936(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105937(3-Hydroxy-4-(10-hydroxy-phenanthren-9-ylazo)-napht...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105939(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105940(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-1,5-dihydro-p...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105942(4-{N'-[1-(3-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105944(3-Hydroxy-4-(2-hydroxy-5-methyl-phenylazo)-naphtha...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105941(4-(2,3-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105943(4-[N'-(1-Benzyl-3-methyl-5-oxo-1,5-dihydro-pyrazol...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105947(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluorometh...)
Affinity DataEC50:  40nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105946(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-3-phenyl-1,5-...)
Affinity DataEC50:  900nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105948(4-{N'-[1-(3-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105949(4-(2,4-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105951(4-(2,6-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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