TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 3.78nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 11.2nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 11.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 17.5nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 22.8nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 28.5nMAssay Description:Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 31.5nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 38.3nMAssay Description:Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 38.4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 40.3nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 44.5nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 52.5nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 56.5nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 74.7nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 75.7nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 475nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 944nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 2.07E+3nMAssay Description:Binding affinity to human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nM ΔG°: -30.1kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) assessed as sparteine oxidationMore data for this Ligand-Target Pair
Affinity DataKi: 1.09E+4nM ΔG°: -28.8kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) assessed as desipramine oxidationMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nM ΔG°: -27.7kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nM ΔG°: -26.9kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nM ΔG°: -26.3kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nM ΔG°: -25.4kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair