Affinity DataKi: 14nMAssay Description:Competitive inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46-400) as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Competitive inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46-400) as substrateMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: <46nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MSK1 as substrate assessed as inhibition of phosphorylation after 60 mins by EL...More data for this Ligand-Target Pair
Affinity DataIC50: <46nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair