BindingDB PrimarySearch_ki

Found 28 with Last Name = 'eyers' and Initial = 'pa'

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)

IC50: 3.5nMT: 2°CAssay Description:Inhibition of Aurora A was assessed in duplicated radiometric assay containing 100uM [gamma-32P] ATP and quantified by p81 phosphocellulose assay.More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)

IC50: 5nMT: 2°CAssay Description:Inhibition of Aurora A was assessed in duplicated radiometric assay containing 100uM [gamma-32P] ATP and quantified by p81 phosphocellulose assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase B(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 18nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 20nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase C(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 25nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

PDB NCI pathway KEGG
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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 49nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1 [1-999,E255K](Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 98nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 100nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 127nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 129nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 150nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 238nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 300nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 320nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 420nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 420nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 591nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1 [1-999,E255K](Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: 1.20E+3nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: 3.10E+3nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: 4.95E+3nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: 8.60E+3nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)

Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: >1.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Cyclin-dependent kinase 1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: >1.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

IC50: >1.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Aurora kinase B(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: >3.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Aurora kinase C(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: >3.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
University Of Sheffield

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: >3.00E+4nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Manchester

PNG

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

IC50: >1.00E+5nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair

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3D Structure (crystal)