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Found 934 with Last Name = 'farrell' and Initial = 'r'
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029704(2-(4-Benzyl-5-oxo-2,5-dihydro-furan-3-yloxymethyl)...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029709(2-(4-Benzyl-2-methyl-5-oxo-2,5-dihydro-furan-3-ylo...)
Affinity DataKi:  0.0160nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029710(4-Isopropyl-6-methoxy-2-(2-methyl-5-oxo-4-phenyl-2...)
Affinity DataKi:  0.0210nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285289(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0220nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029699(2,6-Dichloro-benzoic acid 4-isopropyl-6-methoxy-1,...)
Affinity DataKi:  0.0230nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029717(2-(3-Chloro-6-methyl-2-oxo-2H-pyran-4-yloxymethyl)...)
Affinity DataKi:  0.0250nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029698(4-Isopropyl-6-methoxy-1,1-dioxo-2-(5-oxo-4-phenyl-...)
Affinity DataKi:  0.0250nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029696(2-(3-Benzoyl-6-methyl-2-oxo-2H-pyran-4-yloxymethyl...)
Affinity DataKi:  0.0270nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029712(2-(4-Chloro-5-oxo-2,5-dihydro-furan-3-yloxymethyl)...)
Affinity DataKi:  0.0300nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029713(4-Isopropyl-6-methoxy-1,1-dioxo-2-(3-oxo-cyclobut-...)
Affinity DataKi:  0.0330nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029691(2-(2-Benzyl-3-oxo-cyclopent-1-enyloxymethyl)-4-iso...)
Affinity DataKi:  0.0340nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285280(2,6-Dichloro-benzoic acid 4-ethoxy-6-methoxy-1,1,3...)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029692(4-Isopropyl-6-methoxy-2-(6-methyl-2-oxo-2H-pyran-4...)
Affinity DataKi:  0.0500nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029695(4-Isopropyl-6-methoxy-1,1-dioxo-2-(5-oxo-2,5-dihyd...)
Affinity DataKi:  0.0520nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029711(3-Bromo-2-(4-isopropyl-6-methoxy-1,1,3-trioxo-1,3-...)
Affinity DataKi:  0.0580nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029720(4-Isopropyl-6-methoxy-2-(2-methyl-3-oxo-cyclopent-...)
Affinity DataKi:  0.0600nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029707(3-Chloro-2-(4-isopropyl-6-methoxy-1,1,3-trioxo-1,3...)
Affinity DataKi:  0.0660nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285286(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029721(2-(4-Isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  0.0780nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285283(2,6-Dichloro-benzoic acid 4,6-dimethoxy-1,1,3-trio...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285284(2,6-Dichloro-benzoic acid 4,6-diethoxy-1,1,3-triox...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029715(4-Isopropyl-6-methoxy-1,1-dioxo-2-(3-oxo-3H-inden-...)
Affinity DataKi:  0.0830nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029718(4-Isopropyl-6-methoxy-1,1-dioxo-2-(2-oxo-2H-chrome...)
Affinity DataKi:  0.0900nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029700(4-Isopropyl-6-methoxy-2-(2-methyl-5-oxo-2,5-dihydr...)
Affinity DataKi:  0.0930nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285287(2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029706(2-(4-Isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  0.110nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029716(2-(1-Benzyl-5-oxo-2,5-dihydro-1H-pyrrol-3-yloxymet...)
Affinity DataKi:  0.140nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285290(2,6-Dichloro-benzoic acid 4-ethoxy-1,1,3-trioxo-1,...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029708(4-Isopropyl-6-methoxy-2-(2-methyl-3-oxo-cyclohex-1...)
Affinity DataKi:  0.180nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029702(3-Chloro-2-(4-isopropyl-1,1,3-trioxo-1,3-dihydro-1...)
Affinity DataKi:  0.210nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029693(4-Isopropyl-6-methoxy-1,1-dioxo-2-(2-oxo-2H-thioch...)
Affinity DataKi:  0.220nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285282(2,6-Dichloro-benzoic acid 4-isopropoxy-1,1,3-triox...)
Affinity DataKi:  0.240nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029714(2-(4-Isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  0.25nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029703(4-Isopropyl-6-methoxy-1,1-dioxo-2-(1-phenyl-1H-tet...)
Affinity DataKi:  0.270nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285285(2,6-Dichloro-benzoic acid 6-methoxy-1,1,3-trioxo-4...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285288(2,6-Dichloro-benzoic acid 6-methoxy-1,1,3-trioxo-1...)
Affinity DataKi:  0.470nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029705(4-(4-Isopropyl-6-methoxy-1,1,3-trioxo-1,3-dihydro-...)
Affinity DataKi:  0.5nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029694(2-(4-sec-Butyl-1,1,3-trioxo-1,3-dihydro-1lambda*6*...)
Affinity DataKi:  0.720nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029719(2-(1,6-Dimethyl-2-oxo-1,2-dihydro-pyridin-4-yloxym...)
Affinity DataKi:  0.850nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029701(3-Benzyl-2-(4-isopropyl-6-methoxy-1,1,3-trioxo-1,3...)
Affinity DataKi:  0.900nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50285281(2,6-Dichloro-benzoic acid 4,5-dimethoxy-1,1,3-trio...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039636(2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50029697(3-Chloro-2-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-be...)
Affinity DataKi:  14nMAssay Description:Potency of inhibition of human leukocyte elastase is expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [3H]-dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341370(6-(2,4-Difluorophenoxy)-8-(1-methanesulfonyl-piper...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341366(6-(2,4-Difluorophenoxy)-8-(1,1-dioxo-hexahydro-thi...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341361(6-(2,4-Difluorophenoxy)-8-ethyl-2-(tetrahydro-2H-p...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341350(2-(1-Acetyl-piperidin-4-ylamino)-6-(2,4-difluoroph...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300504(CHEMBL574455 | N-({3-[(5S)-5-tert-butyl-1-[(4-fluo...)
Affinity DataIC50:  1nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50096154(4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-6b-...)
Affinity DataIC50:  1.40nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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