TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 680nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.03E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.19E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.28E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.36E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.42E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.49E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 1.87E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 2.26E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 2.36E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 2.78E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 3.68E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 3.68E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 6.33E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 6.74E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 8.35E+3nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MDM2 (unknown origin) using peptide as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 0.200nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 0.200nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 0.5nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 0.5nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 0.700nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 1nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of Erk1/2 phosphorylation after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 1.10nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Qilu Regor Therapeutics
US Patent
Qilu Regor Therapeutics
US Patent
Affinity DataIC50: 1.5nMAssay Description:The ADP-GLO Kinase Assay (Promega Corp., Madison, WI) measures ADP formed from a kinase reaction. According to the manufacture, the ADP formed in a k...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cells after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.93nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair