Affinity DataKi: 160nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+4nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.93E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.36E+5nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL cells assessed as A23187-stimulated LTB4 production preincubated for 15 mins followed by A23187 addition and measur...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human 5-LOX by cell free assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-LOX in human PMNL cells assessed as A23187-stimulated LTB4 production preincubated for 15 mins followed by A23187 addition and measur...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair