Affinity DataKi: 0.00210nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.00212nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00230nMAssay Description:Tested for inhibition of dihydrofolate reductase enzyme from mouseMore data for this Ligand-Target Pair
Affinity DataKi: 0.00240nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.00260nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.00264nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.00293nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00300nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00300nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00320nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.00340nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00355nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00365nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00520nMAssay Description:Concentration of the compound inhibiting dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00545nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00548nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00550nMAssay Description:Concentration of the compound inhibiting Dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: 0.0120nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: 0.0283nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 990nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity of Dihydrofolate reductase derived from L1210 cell line.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 8.20E+3nMAssay Description:Inhibitory activity of the compound towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Concentration required to inhibit Lactobacillus casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair