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Found 141 with Last Name = 'hangauer' and Initial = 'dg'
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50085448((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307877((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(4-carbami...)
Affinity DataKi:  4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307876((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(4-carbam...)
Affinity DataKi:  10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082643(CHEMBL3423208)
Affinity DataKi:  10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307875((S)-1-((R)-2-amino-4,4-dimethylpentanoyl)-N-(4-car...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307874((S)-1-((R)-2-amino-4-methylpentanoyl)-N-(4-carbami...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307876((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(4-carbam...)
Affinity DataKi:  23nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307872((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(4-carbamim...)
Affinity DataKi:  40nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307856((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(3-chloro...)
Affinity DataKi:  40nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307872((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(4-carbamim...)
Affinity DataKi:  70nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307858((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(3-chlorob...)
Affinity DataKi:  90nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307857((S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(3-chl...)
Affinity DataKi:  100nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307856((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(3-chloro...)
Affinity DataKi:  150nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307873((S)-1-((R)-2-amino-3,3-dimethylbutanoyl)-N-(4-carb...)
Affinity DataKi:  150nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307858((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(3-chlorob...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50536459(CHEMBL4519966)
Affinity DataKi:  200nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  220nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307854((S)-1-((R)-2-amino-4,4-dimethylpentanoyl)-N-(3-chl...)
Affinity DataKi:  410nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307855((S)-1-((R)-2-amino-2-cyclopentylacetyl)-N-(3-chlor...)
Affinity DataKi:  430nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307853((S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorob...)
Affinity DataKi:  540nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307870((S)-1-((R)-2-aminopropanoyl)-N-(4-carbamimidoylben...)
Affinity DataKi:  600nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  750nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307852((S)-1-((R)-2-amino-3,3-dimethylbutanoyl)-N-(3-chlo...)
Affinity DataKi:  920nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307863((S)-N-(4-carbamimidoylbenzyl)-1-(3,3-dimethylbutan...)
Affinity DataKi:  940nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082521(CHEMBL3423005)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50536463(CHEMBL1229851)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307868((S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropa...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307867((S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylprop...)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307864((S)-N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl...)
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082549(CHEMBL3422995)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082652(CHEMBL3423216)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307870((S)-1-((R)-2-aminopropanoyl)-N-(4-carbamimidoylben...)
Affinity DataKi:  1.42E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307866((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclohexylacety...)
Affinity DataKi:  1.49E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307865((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclopentylacet...)
Affinity DataKi:  1.64E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50536464(CHEMBL4561635)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307851((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(3-chlorobe...)
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082651(CHEMBL3423215)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50536468(CHEMBL4585526)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50536467(CHEMBL4547401)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307862((S)-N-(4-carbamimidoylbenzyl)-1-(3-methylbutanoyl)...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50082650(CHEMBL3423214)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307866((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclohexylacety...)
Affinity DataKi:  3.61E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307862((S)-N-(4-carbamimidoylbenzyl)-1-(3-methylbutanoyl)...)
Affinity DataKi:  3.81E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307862((S)-N-(4-carbamimidoylbenzyl)-1-(3-methylbutanoyl)...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307861((S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human alpha-thrombin using chromogenic substrate Pefachrome tPa measured every second for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307861((S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307851((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(3-chlorobe...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307861((S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
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