Affinity DataKi: 0.0130nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.0240nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site
Curated by ChEMBL
Cambridge University Forvie Site
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
Affinity DataKi: 0.0680nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site
Curated by ChEMBL
Cambridge University Forvie Site
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Concentration producing half maximal inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptor in neonatal mouse whole brain (minus cereb...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory activity of the compound against Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit
Curated by ChEMBL
Parke-Davis Research Unit
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit
Curated by ChEMBL
Parke-Davis Research Unit
Curated by ChEMBL
Affinity DataKi: 0.570nMAssay Description:Binding affinity for the Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site
Curated by ChEMBL
Cambridge University Forvie Site
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit
Curated by ChEMBL
Parke-Davis Research Unit
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Binding affinity against Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit
Curated by ChEMBL
Parke-Davis Research Unit
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...More data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site
Curated by ChEMBL
Cambridge University Forvie Site
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Antagonistic activity against cloned human Bombesin receptor bb2 labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells; 0.66-1.3More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit
Curated by ChEMBL
Parke-Davis Research Unit
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibitory activity of the compound against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibitory activity of the compound against Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity for the Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity for the Opioid receptor mu 1More data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Mus musculus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Mus musculus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity of the compound against CCK-A receptorMore data for this Ligand-Target Pair