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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50020938(CHEMBL3287301)

IC50: 1nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair

Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

BDBM109236(WEHI-539)

IC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair

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Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

BDBM109235((E)-2-(8-(2-(Benzo[d]thiazol-2-yl)hydrazono)-5,6,7...)

IC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313807(US10167292, Example 51B)

IC50: 2nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313798(US10167292, Example 42)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339783(CHEMBL1689145 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)

IC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313807(US10167292, Example 51B)

IC50: 3nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)

IC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339781(CHEMBL1689143 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)

IC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Bromodomain-containing protein 2(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313791(US10167292, Example 35)

IC50: 3nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50020936(CHEMBL3287299)

IC50: 4nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Bromodomain-containing protein 2(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313789(US10167292, Example 33)

IC50: 4nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

BDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)

IC50: 5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
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Apoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339783(CHEMBL1689145 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)

IC50: 5nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313798(US10167292, Example 42)

IC50: 6nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313791(US10167292, Example 35)

IC50: 6nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50436680(CHEMBL2398255)

IC50: 6nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339779(CHEMBL1689141 | N-{7-[4-(4'-Chloro-biphenyl-2-ylme...)

IC50: 6nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Bromodomain-containing protein 2(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313807(US10167292, Example 51B)

IC50: 6nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313774(US10167292, Example 8)

PC cid PC sid PDB

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Apoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)

IC50: 6.10nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair

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Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

BDBM109234(6-(8-(2-(Benzo[d]thiazol-2-yl)hydrazono)-5,6,7,8-t...)

IC50: 6.20nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair

PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313775(US10167292, Example 10)

IC50: 7nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Bromodomain-containing protein 2(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313807(US10167292, Example 51B)

IC50: 7nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313779(US10167292, Example 16)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313797(US10167292, Example 41)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313773(US10167292, Example 7)

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Apoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)

IC50: 7nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339777((R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)pipera...)

IC50: 7nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaSCREEN competitive assayMore data for this Ligand-Target Pair

CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50020939(CHEMBL3287302)

IC50: 7nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair

Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

BDBM109236(WEHI-539)

IC50: 7.10nM Kd: 1.40nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Apoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339777((R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)pipera...)

IC50: 8.70nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair

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PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313774(US10167292, Example 8)

IC50: 9nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PC cid PC sid PDB

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Bcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50436679(CHEMBL2398250)

IC50: 10nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313796(US10167292, Example 40)

IC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313791(US10167292, Example 35)

IC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313778(US10167292, Example 13)

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313775(US10167292, Example 10)

IC50: 10nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313773(US10167292, Example 7)

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313779(US10167292, Example 16)

IC50: 11nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313803(US10167292, Example 47)

IC50: 11nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Apoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50339781(CHEMBL1689143 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)

IC50: 12nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-2 by solution competition assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313771(US10167292, Example 5)

IC50: 12nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313791(US10167292, Example 35)

IC50: 12nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM50210164(CHEMBL2132936)

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313777(US10167292, Example 12)

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 3(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313778(US10167292, Example 13)

IC50: 13nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313803(US10167292, Example 47)

IC50: 13nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL

BDBM313795(US10167292, Example 39)