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Found 462 with Last Name = 'humm' and Initial = 'r'
LigandPNGBDBM466723(US10800761, Example 42 | US10800761, Example 55 | ...)
Affinity DataKi: <0.100nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459443(US10752635, Example 4, Peak 1 | US11492354, Exampl...)
Affinity DataKi:  1nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459444(US10752635, Example 4, Peak 2 | US11492354, Exampl...)
Affinity DataKi: <1nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406013(CHEMBL5267188)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM466728(US10800761, Example 47 | US11731958, Example 47)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM466724(US10800761, Example 43 | US11731958, Example 43)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM466705(US10800761, Example 24)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406012(CHEMBL5273201)
Affinity DataKi:  1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM414626(US10435405, Example 43 | US10934288, Example 43)
Affinity DataKi: <1nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406009(CHEMBL5284132)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405947(CHEMBL5274764)
Affinity DataKi:  1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405892(CHEMBL5267747)
Affinity DataKi: <1nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405896(CHEMBL5281003)
Affinity DataKi: <1nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataKi: <1nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405898(CHEMBL5283973)
Affinity DataKi: <1nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405899(CHEMBL5288420)
Affinity DataKi: <1nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM459445(US10752635, Example 5, Peak 1 | US11492354, Exampl...)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406008(CHEMBL5276026)
Affinity DataKi:  1.5nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405900(CHEMBL5268277)
Affinity DataKi:  1.60nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)
Affinity DataKi:  1.70nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459439(US10752635, Example 1, Peak 2 | US11492354, Exampl...)
Affinity DataKi:  1.80nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM466687(US10800761, Example 6 | US11731958, Example 6 | US...)
Affinity DataKi:  1.90nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM466727(US10800761, Example 46 | US11731958, Example 46)
Affinity DataKi:  2nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405796(CHEMBL5277555)
Affinity DataKi:  2nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405895(CHEMBL5279971)
Affinity DataKi:  2nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM466682(US10800761, Example 1 | US11731958, Example 1)
Affinity DataKi:  2.20nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459441(US10752635, Example 3, Peak 1 | US11492354, Exampl...)
Affinity DataKi:  2.20nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459484(US10752635, Example 35 | US11492354, Example 35)
Affinity DataKi:  2.20nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM498971(US11014929, Example 11 | US11542265, Example 11)
Affinity DataKi:  2.5nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405893(CHEMBL5271378)
Affinity DataKi:  2.60nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM414751(US10435405, Example 168 | US10934288, Example 168)
Affinity DataKi:  2.70nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM536101(US11242343, Example 8 | US11891388, Example 8)
Affinity DataKi:  3nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405792(CHEMBL5281791)
Affinity DataKi:  3nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405894(CHEMBL5269770)
Affinity DataKi:  3nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405946(CHEMBL5279231)
Affinity DataKi:  3.30nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM414714(US10435405, Example 131 | US10934288, Example 131)
Affinity DataKi:  3.5nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406004(CHEMBL5267479)
Affinity DataKi:  3.90nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM414772(US10435405, Example 189 | US10435405, Example 190 ...)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414765(5-(4-(Azetidin-1-ylmethyl)- 2-fluoro-6-methylpheny...)
Affinity DataKi:  4.10nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414757(US10435405, Example 174 | US10435405, Example 175 ...)
Affinity DataKi:  4.60nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414759(US10435405, Example 176 | US10934288, Example 176)
Affinity DataKi:  5nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)
Affinity DataKi:  5.40nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50406010(CHEMBL5277513)
Affinity DataKi:  7.10nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM498974(US11014929, Example 14 | US11542265, Example 14)
Affinity DataKi:  12nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405891(CHEMBL5290431)
Affinity DataKi:  22nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataKi:  23nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in guinea pig trachea in the presence of 11,9-epoxymethano-PGH2More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM536097(US11242343, Example 4 | US11891388, Example 4)
Affinity DataKi:  28nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405896(CHEMBL5281003)
Affinity DataKi:  36nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in guinea pig trachea in the presence of 9,11-azo-PGH2More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM466723(US10800761, Example 42 | US10800761, Example 55 | ...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50405895(CHEMBL5279971)
Affinity DataKi:  64nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in rat aorta in the presence of 11,9-epoxymethano-PGH2More data for this Ligand-Target Pair
In DepthDetails
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