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Found 190 with Last Name = 'imahori' and Initial = 't'
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataKi:  85nMAssay Description:Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)
Affinity DataKi:  460nMAssay Description:Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  32nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  32nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human lysosomal beta-glucosidaseMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  70nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  100nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen debranching enzyme(Oryctolagus cuniculus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rabbit muscle amylo-1,6-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333457((2S,3S,4S,5S)-2-hexyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333457((2S,3S,4S,5S)-2-hexyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat intestinal isomaltase using isomoltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  170nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  180nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  180nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333456((2S,3S,4S,5S)-2-(hydroxymethyl)-5-pentylpyrrolidin...)
Affinity DataIC50:  190nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50399654(CHEMBL2177691)
Affinity DataIC50:  190nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen debranching enzyme(Oryctolagus cuniculus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  190nMAssay Description:Inhibition of rabbit muscle amylo-1,6-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333456((2S,3S,4S,5S)-2-(hydroxymethyl)-5-pentylpyrrolidin...)
Affinity DataIC50:  190nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50399655(CHEMBL2177690)
Affinity DataIC50:  220nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333458((2S,3S,4S,5S)-2-heptyl-5-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333458((2S,3S,4S,5S)-2-heptyl-5-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  240nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399654(CHEMBL2177691)
Affinity DataIC50:  240nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333454((2S,3S,4S,5S)-2-(hydroxymethyl)-5-propylpyrrolidin...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333454((2S,3S,4S,5S)-2-(hydroxymethyl)-5-propylpyrrolidin...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of rat intestinal isomaltase using isomoltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat intestinal isomaltase using isomoltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399655(CHEMBL2177690)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333459((2S,3S,4S,5S)-2-(hydroxymethyl)-5-octylpyrrolidine...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333459((2S,3S,4S,5S)-2-(hydroxymethyl)-5-octylpyrrolidine...)
Affinity DataIC50:  320nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  350nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375511(CHEMBL406973)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat intestinal isomaltase using isomoltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  370nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  370nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50333458((2S,3S,4S,5S)-2-heptyl-5-(hydroxymethyl)pyrrolidin...)
Affinity DataIC50:  380nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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