Affinity DataKi: 90nMAssay Description:Inhibitory activity against L-arginine binding to Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HPGDSMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.34nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mPGES-1 in human fetal fibroblast cells assessed as PGF2alpha level after 50 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.26nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
G. D. Searle Research And Development
Curated by ChEMBL
G. D. Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
G. D. Searle Research And Development
Curated by ChEMBL
G. D. Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of cloned (from RNA) human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair