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Found 818 with Last Name = 'jun' and Initial = 'f'
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26305(4-aminopyrazole quinazoline, 5 | N-(3-fluorophenyl...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26307(4-aminopyrazole quinazoline, 7 | N-(3-fluorophenyl...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26308(4-aminopyrazole quinazoline, 8 | N-(2,3-difluoroph...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26277(N-(3,5-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26284(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26285(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2S)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26286(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26287(N-(2,3-difluorophenyl)-2-[3-({7-[3-(4-hydroxypiper...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26288(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26289(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26290(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)am...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26291(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(m...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26292(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26294(CHEMBL214848 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26295(CHEMBL214849 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26296(CHEMBL216053 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26297(CHEMBL215322 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26298(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethy...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26299(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26301(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(p...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26302(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26303(4-aminopyrazole quinazoline, 3 | N-(2,3-difluoroph...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26304(4-aminopyrazole quinazoline, 4 | N-(2,3-difluoroph...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26293(CHEMBL217804 | N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26274(CHEMBL216769 | N-(3-fluorophenyl)-2-{3-[(7-{3-[4-(...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26276(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  4.60nMAssay Description:In vitro inhibition constant for Aurora-CMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26278(N-(3-chlorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26282(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26283(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  13nM ΔG°:  -44.6kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26273(N-(2-fluorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26272(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26296(CHEMBL216053 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  18nMAssay Description:In vitro inhibition constant for Aurora-BMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26275(N-(4-fluorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition constant for FLT-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26285(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2S)-2-(hydrox...)
Affinity DataKi:  39nM ΔG°:  -42.3kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26280(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  39nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26286(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi:  55nM ΔG°:  -41.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26291(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(m...)
Affinity DataKi:  65nM ΔG°:  -41.0kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26279(N-(3-cyanophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)pi...)
Affinity DataKi:  83nM ΔG°:  -40.0kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26295(CHEMBL214849 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi:  87nM ΔG°:  -40.3kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26284(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)
Affinity DataKi:  94nM ΔG°:  -40.1kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26289(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi:  110nM ΔG°:  -39.7kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26281(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26297(CHEMBL215322 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)
Affinity DataKi:  160nM ΔG°:  -38.8kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM26292(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)
Affinity DataKi:  190nM ΔG°:  -38.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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