Affinity DataIC50: 0.140nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.630nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.830nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha
US Patent
Chugai Seiyaku Kabushiki Kaisha
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human FTaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory of Candida albicans chitin synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair