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Found 146 with Last Name = 'kreft' and Initial = 'a'
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006816((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...)
Affinity DataKi:  60nMAssay Description:The compound was tested for binding affinity against Cysteinyl leukotriene D4 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity towards Cysteinyl leukotriene D4 receptor antagonist in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229761(CHEMBL314337 | L-689037)
Affinity DataIC50:  2nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Mus musculus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229760(CHEMBL316184 | WAY-121520)
Affinity DataIC50:  4nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  5nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in rat RBL-2H3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory activity against human synovial fluid phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]-arachidonic acid labeled E. co...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50004679(2-Benzyl-naphthalen-1-ol | 2-Benzyl-naphthalen-1-o...)
Affinity DataIC50:  19nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006807(4-({(3-Fluoro-benzyl)-[4-(quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50:  20nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  47nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in RBL-2H3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  60nMAssay Description:The compound was tested for inhibitory activity against LT synthesis in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006796(CHEMBL82843 | LY-233569 | Sodium;(2E)-N-hydroxy-N-...)
Affinity DataIC50:  100nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  100nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006814(2-[6-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-propi...)
Affinity DataIC50:  130nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS] (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
Affinity DataIC50:  140nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50001183(3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50:  150nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50480807(CHEMBL576553)
Affinity DataIC50:  154nMAssay Description:Displacement of [3H](S)-5-chloro-N-(3-ethyl-1-hydroxypentan-2-yl)thiophene-2-sulfonamide from gamma secretase in human SH-SY5Y cells after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  160nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS] (in vivo)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  200nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in mouse macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016627(C,C,C-Trifluoro-N-[7-(quinolin-2-ylmethoxy)-naphth...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006815(4,6-Dimethyl-2-(6-phenyl-hexylamino)-pyrimidin-5-o...)
Affinity DataIC50:  300nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  300nMAssay Description:Ability to inhibit 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518789(CHEMBL4473548)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006819(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-aceta...)
Affinity DataIC50:  350nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  400nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  460nMAssay Description:Inhibition of ADH1 (unknown origin) preincubated for 2 hrs followed by substrate/NAD+ additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006793(1-Ethyl-3-{4-[4-(4-hydroxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  500nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  500nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50:  500nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  530nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518789(CHEMBL4473548)
Affinity DataIC50:  540nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged ABL2 (M1 to P650 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006810(4-[4-(2,5-Dimethyl-pyrrol-1-yl)-phenyl]-but-3-enoi...)
Affinity DataIC50:  600nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in guinea pig polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  685nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged ABL2 (M1 to P650 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  800nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 (K784 to I1338 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006801(CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006801(CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...)
Affinity DataIC50:  1.40E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase receptor in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006798(2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...)
Affinity DataIC50:  2.00E+3nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50220291(1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylpiper...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006822(1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethox...)
Affinity DataIC50:  2.00E+3nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518789(CHEMBL4473548)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 (K784 to I1338 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006822(1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethox...)
Affinity DataIC50:  2.40E+3nMAssay Description:Ability to inhibit 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006791(CHEMBL83977 | {3-[3-(1-Hydroxy-hexyl)-phenoxymethy...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50:  3.00E+3nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged c-KIT (T544 to V976 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration to inhibit Prostaglandin G/H synthase in the ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006820(2-[3-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quino...)
Affinity DataIC50:  3.90E+3nMAssay Description:Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006821(4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...)
Affinity DataIC50:  3.90E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged VEGFR3 (N799 to R1298 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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