Compile Data Set for Download or QSAR
maximum 50k data
Found 41 with Last Name = 'krstenansky' and Initial = 'jl'
TargetProthrombin(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50037906(CHEMBL439487 | MDL-28050 | Suc-Tyr-Glu-Pro-Ile-Pro...)
Affinity DataKi:  100nMAssay Description:Binding affinity values determined by clotting inhibition assaysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50037905(3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1oxy-NH...)
Affinity DataKi:  100nMAssay Description:Binding affinity values determined by clotting inhibition assaysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50037907(Antraniloyl-NH-(Ch2)7-CO-Asp-Tyr-Glu-Pro-Ile-Pro-G...)
Affinity DataKi:  100nMAssay Description:Binding affinity values determined by clotting inhibition assaysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50037908(1,5,dansyl-NH-(Ch2)7-CO-Asp-Tyr-Glu-Pro-Ile-Pro-Gl...)
Affinity DataKi:  100nMAssay Description:Binding affinity values determined by clotting inhibition assaysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50037906(CHEMBL439487 | MDL-28050 | Suc-Tyr-Glu-Pro-Ile-Pro...)
Affinity DataIC50:  29nMAssay Description:Inhibitory concentration of the compound against Thrombin; 0.029-0.15 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein E6(Human papillomavirus type 16)
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  850nMAssay Description:Inhibition of GST-tagged Human papillomavirus 16 protein E6 interaction with His-tagged human caspase 8 expressed in Escherichia coli after 1 hr incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024617(N-acetylhirudin45-65)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024619([Tyr56] Hirudin55-65)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50023468(Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln | ...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein E6(Human papillomavirus type 16)
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of GST-tagged Human papillomavirus 16 protein E6 interaction with His-tagged human caspase 8 expressed in Escherichia coli after 1 hr incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50023470(Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln | Hiru...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024618([Leu59] Hirudin54-65)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024613([Ala58] Hirudin55-65)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024616(CHEMBL415171 | [Ala63] Hirudin55-65)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024609([Sar60] Hirudin54-65)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024612([Ala61] Hirudin55-65)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024610([Ala65] Hirudin55-65)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein E6(Human papillomavirus type 16)
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GST-tagged Human papillomavirus 16 protein E6 interaction with His-tagged human caspase 8 expressed in Escherichia coli after 1 hr incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein E6(Human papillomavirus type 16)
Loma Linda University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GST-tagged Human papillomavirus 16 protein E6 interaction with His-tagged human caspase 8 expressed in Escherichia coli after 1 hr incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024623(CHEMBL2372582)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024615([Ala62] Hirudin55-65)
Affinity DataIC50:  4.28E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024620(CHEMBL268122 | [Glu63,Ala65] Hirudin55-65)
Affinity DataIC50:  5.91E+4nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024621([Ala60] Hirudin55-65)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50226977(CHEMBL1160128)
Affinity DataIC50: <2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024622([Ala64] Hirudin55-65)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024611([Ala57] Hirudin55-65)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024614([Ala59] Hirudin55-65)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50226976(CHEMBL1160129)
Affinity DataIC50: <2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50226975(CHEMBL1160104)
Affinity DataIC50: <2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50024624([D-Leu,Ala65] Hirudin55-65)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of plasma fibrin clot formation by thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289763(1N-{4-[1-cyclohexylamino(cyclohexylimino)methylami...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289768(CHEMBL294452 | Tributyl-{4-[(S)-2-(N',N''-dicycloh...)
Affinity DataKd:  540nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289765(CHEMBL292816 | Tributyl-{4-[(R)-2-(N',N''-dicycloh...)
Affinity DataKd:  290nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289770((S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexy...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289772(5-Aminomethyl-2-[(S)-2-(N',N''-dicyclohexyl-guanid...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289766(CHEMBL555235 | Tributyl-{4-[(S)-2-(3-cyclohexyl-ur...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289775((R)-2-(N',N''-Dicyclohexyl-guanidino)-N-(4-guanidi...)
Affinity DataKd:  860nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289776(CHEMBL539631 | Tributyl-{4-[(S)-2-(N',N''-dicycloh...)
Affinity DataKd:  670nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289777((S)-2-(N',N''-Dicyclohexyl-guanidino)-N-[4-(N',N''...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289769(CHEMBL555236 | Tributyl-{4-[(R)-2-(N',N''-dicycloh...)
Affinity DataKd:  370nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289778((S)-2-(N',N''-Dicyclohexyl-guanidino)-N-(4-guanidi...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1, activity expressed as KdMore data for this Ligand-Target Pair
In DepthDetails Article