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Found 280 with Last Name = 'kukolj' and Initial = 'g'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142042((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  8nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  15nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193054(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-indole-6-c...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142043((2S)-3-(5-(carboxymethoxy)-1H-indol-3-yl)-2-(1-cyc...)
Affinity DataIC50:  19nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142041(3-{(S)-2-Carboxy-2-[(1-cyclohexyl-2-furan-3-yl-1H-...)
Affinity DataIC50:  20nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193050(3-cyclopentyl-2-(furan-3-yl)-1-methyl-1H-indole-6-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193059(3-cyclopentyl-2-(furan-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193060(3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50162092(3-Cyclohexyl-1-methyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142056((S)-3-(5-Carbamoyl-1H-indol-3-yl)-2-[(1-cyclohexyl...)
Affinity DataIC50:  37nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193057(1-cyclohexyl-2-(furan-3-yl)-3-methyl-1H-indole-5-c...)
Affinity DataIC50:  44nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50162094(3-Cyclohexyl-2-phenyl-1H-indole-6-carboxylic acid ...)
Affinity DataIC50:  50nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142052((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  50nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193069(3-cyclohexyl-2-(furan-3-yl)-1-methyl-1H-pyrrolo[2,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50:  60nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193063(3-cyclopentyl-2-(furan-3-yl)-7-hydroxy-1-methyl-1H...)
Affinity DataIC50:  75nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193055(3-cyclopentyl-2-(furan-3-yl)benzo[b]thiophene-6-ca...)
Affinity DataIC50:  78nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193052(3-cyclohexyl-1-methyl-2-phenyl-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50:  80nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193064(3-cyclopentyl-2-(furan-3-yl)benzofuran-6-carboxyli...)
Affinity DataIC50:  81nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193062(3-cyclohexyl-1-methyl-2-(pyridin-2-yl)-1H-indole-6...)
Affinity DataIC50:  90nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142053((S)-3-(5-Amino-1H-indol-3-yl)-2-[(1-cyclohexyl-2-f...)
Affinity DataIC50:  90nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142044((S)-3-[5-(1-Carboxy-1-methyl-ethoxy)-1H-indol-3-yl...)
Affinity DataIC50:  100nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142049((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  120nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142050((S)-2-(1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]im...)
Affinity DataIC50:  140nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142048((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  150nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50370756(CHEMBL1789968)
Affinity DataIC50:  150nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142069((R)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  160nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193053(1-cyclohexyl-3-methyl-2-phenyl-1H-indole-5-carboxy...)
Affinity DataIC50:  180nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193067(3-cyclohexyl-2-(pyridin-2-yl)-1H-indole-6-carboxyl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193051(7-chloro-3-cyclopentyl-2-(furan-3-yl)-1-methyl-1H-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50437045(CHEMBL2403225)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398047(CHEMBL2181641)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193066(3-cyclopentyl-2-(furan-3-yl)-7-methoxy-1-methyl-1H...)
Affinity DataIC50:  340nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142051((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398051(CHEMBL2181777)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50158528((S)-1-cyclohexyl-2-(furan-3-yl)-N-(2-(5-hydroxy-1H...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human liver CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142064((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142065(CHEMBL177283 | [(1-Cyclohexyl-2-furan-3-yl-1H-benz...)
Affinity DataIC50:  400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50158528((S)-1-cyclohexyl-2-(furan-3-yl)-N-(2-(5-hydroxy-1H...)
Affinity DataIC50:  440nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142057(2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-...)
Affinity DataIC50:  460nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193058(3-cyclopentyl-2-(furan-3-yl)-7-(methoxycarbonyl)-1...)
Affinity DataIC50:  480nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142062((R)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50:  700nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398049(CHEMBL2181635)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50193049(1-cyclohexyl-3-methyl-2-(pyridin-2-yl)-1H-indole-5...)
Affinity DataIC50:  820nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398045(CHEMBL2181618)
Affinity DataIC50:  900nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398050(CHEMBL2181634)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50433324(CHEMBL2375371)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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