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Found 376 with Last Name = 'lópez' and Initial = 'mg'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  20.2nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(CHEMBL1087194 | ethyl 5-amino-2-methyl-6,7,8,9-tet...)
Affinity DataKi:  24nMAssay Description:Inhibition of AChE (unknown orign) by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262340(11-Amino-3,3-dimethyl-12-p-tolyl-3,4,5,7,8,9,10,12...)
Affinity DataKi:  38.9nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262341(11-Amino-12-(4-methoxy-phenyl)-3,3-dimethyl-3,4,5,...)
Affinity DataKi:  41.9nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262282(11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-...)
Affinity DataKi:  61.3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262339(11-Amino-12-(4-fluoro-phenyl)-3,3-dimethyl-3,4,5,7...)
Affinity DataKi:  106nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50384793(CHEMBL2037384)
Affinity DataKi:  155nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262342(11-Amino-3,3-dimethyl-12-pyridin-4-yl-3,4,5,7,8,9,...)
Affinity DataKi:  157nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  428nMAssay Description:Competitive inhibition of Electrophorus electricus AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM31904(CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM31904(CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...)
Affinity DataKi:  8.60E+3nMAssay Description:Binding affinity to Electrophorus electricus AChE peripheral anionic siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM31904(CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity to Electrophorus electricus AChE peripheral anionic siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50324068(2-Chloro-6-(piperidin-1-yl)pyridine-3,5-dicarbonit...)
Affinity DataKi:  1.72E+4nMAssay Description:Non competitive inhibition of Electrophorus electricus AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50322767(2-Methyl-7-{[8-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50322768(5-Chloro-7-{[9-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002644(2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  1.40nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322767(2-Methyl-7-{[8-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002628(4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-p...)
Affinity DataIC50:  2.90nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50:  2.90nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002603(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  3.30nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002613(2,6-Dimethyl-4-(2-trifluoromethyl-phenyl)-1,4-dihy...)
Affinity DataIC50:  3.60nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322766(7-{[9-(1,2,3,4-Tetrahydroacridin-9-ylamino)nonylam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002607(4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-p...)
Affinity DataIC50:  5.10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002626(2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  5.10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of horse serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of Equus caballus BChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50322766(7-{[9-(1,2,3,4-Tetrahydroacridin-9-ylamino)nonylam...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322767(2-Methyl-7-{[8-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322768(5-Chloro-7-{[9-(1,2,3,4-tetrahydroacridin-9-ylamin...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322777(2-Methyl-7-{[10-(1,2,3,4-tetrahydroacridin-9-ylami...)
Affinity DataIC50:  7nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002600(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  7.80nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of BuChE in horse serum using butyrylthiocholine as substrate by Ellman methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002643(4-(2-Chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyrid...)
Affinity DataIC50:  10nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of BuChE in horse serum by Ellman methodMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002635(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  13nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  13.4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50333148(5-Amino-2-(dimethylamino)-6,7,8,9-tetrahydrobenzo[...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002621(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  15nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322766(7-{[9-(1,2,3,4-Tetrahydroacridin-9-ylamino)nonylam...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322766(7-{[9-(1,2,3,4-Tetrahydroacridin-9-ylamino)nonylam...)
Affinity DataIC50:  20nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM50322770(7-{[7-(1,2,3,4-Tetrahydroacridin-9-ylamino)heptyla...)
Affinity DataIC50:  25nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002631(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  25nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter

Curated by ChEMBL
LigandPNGBDBM50002580(2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  25nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50333150(5-Amino-2-piperidin-1-yl-6,7,8,9-tetrahydrobenzo[1...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  27nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Quimica Medica

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  27nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
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