TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Reversible inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Reversible inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using dGTP as substrate measured after 30 mins by mala...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using dGTP as substrate measured after 30 mins by mala...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair