Compile Data Set for Download or QSAR
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Found 14 with Last Name = 'leone' and Initial = 'm'
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM85274(BI-21C6)
Affinity DataIC50:  500nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50133355(2,3,8-Trihydroxy-9-oxo-9H-benzocycloheptene-6-carb...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM85272(BI-21C4)
Affinity DataIC50:  3.30E+3nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM85273(BI-21C5)
Affinity DataIC50:  5.10E+3nM Kd:  1.98E+4nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM85275(BI-21C7)
Affinity DataIC50:  5.70E+3nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50133357(2,3,8-Trihydroxy-9-oxo-9H-benzocycloheptene-6-carb...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50133353(2,3,8-Trihydroxy-9-oxo-9H-benzocycloheptene-6-carb...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50133356(2-Hydroxy-3,4,6-trimethoxy-benzocyclohepten-5-one ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50133358(2,3,4,6-Tetramethoxy-benzocyclohepten-5-one | CHEM...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against Bcl-xlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50540551(CHEMBL4641893)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human N-terminal His-tagged JAK2 catalytic domain (826 to 1132 end residues) at 25 degree C by microscale thermophoresis assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50578550(CHEMBL4857393)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to N-terminal His-tagged human JAK2 catalytic domain (826 to 1132 residues) expressed in baculovirus-infected Sf21 cells by Microsca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50578551(CHEMBL4851880)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to N-terminal His-tagged human JAK2 catalytic domain (826 to 1132 residues) expressed in baculovirus-infected Sf21 cells by Microsca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed