Affinity DataIC50: <0.5nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of CHK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of ALK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of horse serum butyrylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of ZAP70 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LCK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of rat plasma butyrylcholine esterase in presence of butyrylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration required against acetylcholinesterase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of rat brain acetylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of ALK using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate a...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of CHK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Inhibition of c-Src using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration required against acetylcholinesterase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 184nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of rat brain acetylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 405nMAssay Description:Inhibition of c-Met using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
Affinity DataIC50: 607nMAssay Description:Inhibition of RSK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in CHO cells assessed as blockade of carbachol-induced inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human muscarinic M4 receptor expressed in CHO cells assessed as blockade of carbachol-induced inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of Aurora A using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence micropl...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of horse serum butyrylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of electric eel acetylcholine esterase type V-S in presence of acetylcholine substrate by chemiluminescent assayChecked by AuthorMore data for this Ligand-Target Pair