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Dual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL

BDBM50512456(CHEMBL4469414)

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50073585(CHEMBL3408945 | US10358436, Example A102 | US99078...)

Ki: 0.100nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50369383(CHEMBL1788222)

Ki: 0.230nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50073587(CHEMBL3408947 | US10358436, Example A185 | US20230...)

Ki: 0.260nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)

Ki: 0.260nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50369383(CHEMBL1788222)

Ki: 0.420nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)

Ki: 0.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Vasopressin V1b receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

BDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)

Ki: 0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)

Ki: 0.650nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)

Ki: 0.670nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL

BDBM50081537(CHEMBL3422092)

Ki: 0.700nMAssay Description:Competitive inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate by Lineweaver-Burk plot analysis in prese...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50073586(CHEMBL3408946 | US10358436, Example A198 | US99078...)

Ki: 0.730nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Dual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL

BDBM50183019(CHEMBL3819210)

Ki: 0.770nMAssay Description:Competitive inhibition of TTK (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair

Vasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL

BDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)

Ki: 1nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

Beta-secretase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50392835(CHEMBL2151181)

Ki: <1nMAssay Description:Inhibition of human recombinant BACE2 by FRET assayMore data for this Ligand-Target Pair

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Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)

Ki: 1.10nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50369382(CHEMBL1788223)

Ki: 1.40nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50369382(CHEMBL1788223)

Ki: 1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Alpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University

Curated by ChEMBL

BDBM50369382(CHEMBL1788223)

Ki: 1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Beta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50392835(CHEMBL2151181)

Ki: 1.70nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair

CHEMBL MMDB PC cid PC sid Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309061(CHEMBL591541 | N-(((3R,6S)-1-(4-chlorophenyl)-6-(2...)

Ki: 2.30nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)

Ki: 2.40nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM3033(3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...)

Ki: 3.40nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309047(CHEMBL591352 | N-(2-((3S,6S)-1-(4-chlorophenyl)-6-...)

Ki: 3.80nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50369382(CHEMBL1788223)

Ki: 3.90nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)

Ki: 4.20nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)

Ki: 4.20nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309046(CHEMBL591994 | N-(2-((3S,6S)-1-(4-chlorophenyl)-6-...)

Ki: 4.20nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309049(CHEMBL591542 | N-(((3S,6S)-1-(4-chlorophenyl)-6-(2...)

Ki: 5nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309043(CHEMBL591067 | N-(2-((3S,6S)-1-(4-chlorophenyl)-6-...)

Ki: 5.10nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

Alpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)

Ki: 5.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309045(CHEMBL603529 | N-(2-((3S,6S)-1-(4-chlorophenyl)-6-...)

Ki: 5.80nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309050(CHEMBL591540 | N-(((3R,6S)-1-(4-chlorophenyl)-6-(2...)

Ki: 6nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309030((3R,6S)-1-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-...)

Ki: 6.30nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Beta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50392836(CHEMBL2151141)

Ki: 7.80nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309041(CHEMBL601936 | tert-butyl 4-(((3S,6S)-1-(4-chlorop...)

Ki: 8nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Beta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50392837(CHEMBL2151182)

Ki: 8nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309027((3R,6S)-1-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-...)

Ki: 9.10nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)

Ki: 11nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)

Ki: 11nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50426474(CHEMBL1980391)

Ki: 11nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309036(1-(4-(((3S,6S)-1-(4-chlorophenyl)-6-(2,4-dichlorop...)

Ki: 13nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309054(CHEMBL592628 | trans-1-(4-chlorophenyl)-2-(2,4-dic...)

Ki: 15nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
National Taiwan University

Curated by ChEMBL

BDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)

Ki: 16nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309028((2S,5R)-1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-...)

Ki: 16nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

Vasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL

BDBM50299342(CHEMBL1204126 | CHEMBL1204403 | CHEMBL572709 | N-(...)

Ki: 16nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50309033((3R,6S)-1-(4-chlorophenyl)-N-cyclohexyl-6-(2,4-dic...)

Ki: 18nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Oxytocin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL

BDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)

Ki: 19nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair

Vasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL

BDBM50299342(CHEMBL1204126 | CHEMBL1204403 | CHEMBL572709 | N-(...)

Ki: 21nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair