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Found 175 with Last Name = 'lin' and Initial = 'ce'
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50229232(CHEMBL610527)
Affinity DataKi:  0.00500nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50229232(CHEMBL610527)
Affinity DataKi:  0.0100nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor kappa using [3H]-EK as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM82552(CAS_111555-58-9 | NTB | naltrindolebenzofuran)
Affinity DataKi:  0.0130nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50451343(CHEMBL477154)
Affinity DataKi:  0.0180nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50370067(CHEMBL1237164)
Affinity DataKi:  0.0310nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50041573(17-(cyclopropylmethyl)-17'-butyl-6,6',7,7'-tetrade...)
Affinity DataKi:  0.0400nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50229231(CHEMBL610534)
Affinity DataKi:  0.0540nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136352(US8859534, 38)
Affinity DataKi:  0.0640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136326(US8859534, 12)
Affinity DataKi:  0.110nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136354(US8859534, 40)
Affinity DataKi:  0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136317(US8859534, 3)
Affinity DataKi:  0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136325(US8859534, 11)
Affinity DataKi:  0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136363(US8859534, 49)
Affinity DataKi:  0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136362(US8859534, 48)
Affinity DataKi:  0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136318(US8859534, 4)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136361(US8859534, 47)
Affinity DataKi:  0.220nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136365(US8859534, 51)
Affinity DataKi:  0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136351(US8859534, 37)
Affinity DataKi:  0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  0.260nMAssay Description:Binding affinity of compound was measured against Opioid receptor kappa 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  0.280nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136322(US8859534, 8)
Affinity DataKi:  0.280nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136322(US8859534, 8)
Affinity DataKi:  0.290nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136353(US8859534, 39)
Affinity DataKi:  0.320nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136357(US8859534, 43)
Affinity DataKi:  0.330nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136359(US8859534, 45)
Affinity DataKi:  0.340nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136367(US8859534, 53)
Affinity DataKi:  0.350nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50041568(17-(cyclopropylmethyl)-17'-[2-[(carbobenzyloxy)ami...)
Affinity DataKi:  0.360nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136324(US8859534, 10)
Affinity DataKi:  0.380nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009129(binaltorphimine(BNI))
Affinity DataKi:  0.410nMAssay Description:Binding affinity against Opioid receptor kappa 1 was measured in the guinea pig brain membranes using [3H]EK in the presence of 1 uM unlabeled DAMGO ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136338(US8859534, 24)
Affinity DataKi:  0.420nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136364(US8859534, 50)
Affinity DataKi:  0.430nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136323(US8859534, 9)
Affinity DataKi:  0.440nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136350(US8859534, 36)
Affinity DataKi:  0.460nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136317(US8859534, 3)
Affinity DataKi:  0.520nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136327(US8859534, 13)
Affinity DataKi:  0.550nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136338(US8859534, 24)
Affinity DataKi:  0.560nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136321(US8859534, 7)
Affinity DataKi:  0.590nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50041572(17-(cyclopropylmethyl)-17'-(2-guanidinoethyl-6,6',...)
Affinity DataKi:  0.590nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50009222(4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)...)
Affinity DataKi:  0.630nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pigbrain membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136356(US8859534, 42)
Affinity DataKi:  0.640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136332(US8859534, 18)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.760nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136330(US8859534, 16)
Affinity DataKi:  0.780nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50229230(CHEMBL610007)
Affinity DataKi:  0.840nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136342(US8859534, 28)
Affinity DataKi:  0.850nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136326(US8859534, 12)
Affinity DataKi:  0.880nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136324(US8859534, 10)
Affinity DataKi:  0.890nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136336(US8859534, 22)
Affinity DataKi:  0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136340(US8859534, 26)
Affinity DataKi:  0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science

US Patent
LigandPNGBDBM136333(US8859534, 19)
Affinity DataKi:  0.990nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
In DepthDetails US Patent
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