Affinity DataKi: 0.00500nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor kappa using [3H]-EK as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0540nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.0640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.110nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.200nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.220nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding affinity of compound was measured against Opioid receptor kappa 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric p...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.280nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.290nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.320nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.330nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.340nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.350nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.380nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Binding affinity against Opioid receptor kappa 1 was measured in the guinea pig brain membranes using [3H]EK in the presence of 1 uM unlabeled DAMGO ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.420nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.430nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.440nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.460nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.520nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.550nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.560nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.590nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pigbrain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.700nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.780nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.850nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.880nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.890nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.990nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair