Compile Data Set for Download or QSAR
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Found 182 with Last Name = 'llinas-brunet' and Initial = 'm'
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053967((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[3-(1-ethyl-p...)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033458((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-(2-Benzyl-3-phen...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033457(1-[(S)-((S)-1-Carboxy-3-methyl-butylcarbamoyl)-((S...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50369164(CHEMBL1169533)
Affinity DataIC50:  2nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50369164(CHEMBL1169533)
Affinity DataIC50:  2nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053968((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[3-(1-ethyl-p...)
Affinity DataIC50:  3nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50050831((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[3-(1-ethyl-p...)
Affinity DataIC50:  3nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033463((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3,3-dimethyl-2-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053981((S)-2-((S)-3-Carboxy-2-{(2R,5S)-2-(3,3-dimethyl-2-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033465((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[(S)...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053973((S)-3-((S)-2-{(S)-2-[3-(1-Ethyl-propyl)-ureido]-3,...)
Affinity DataIC50:  6nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033453(1-((S)-((S)-1-Carboxy-3-methyl-butylcarbamoyl)-{(S...)
Affinity DataIC50:  6.40nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50050828((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[3-(...)
Affinity DataIC50:  7nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053984((S)-2-{(S)-3-Carboxy-2-[(2S,5S)-5-[3-(1-ethyl-prop...)
Affinity DataIC50:  7nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033470((S)-2-{(S)-3-Carboxy-2-[(S)-2-((S)-3-methyl-2-{(S)...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137962((1R,2S)-1-((3R,5S)-1-((S)-2-((S)-2-acetamido-2-cyc...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50050826((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[3-(1-ethyl-p...)
Affinity DataIC50:  15nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053962((S)-N-((R)-1-Ethyl-2,2-dimethyl-propyl)-3-((S)-2-{...)
Affinity DataIC50:  18nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50369165(CHEMBL1169532)
Affinity DataIC50:  20nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033477((S)-2-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(2-Benzyl-3-phe...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033456((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[(S)-2-cycloh...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033462((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[(S)...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033462((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[(S)...)
Affinity DataIC50:  24nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053963((S)-3-((S)-2-{(S)-2-[3-(1-Ethyl-propyl)-ureido]-3,...)
Affinity DataIC50:  27nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50175297(CHEMBL3810245)
Affinity DataIC50:  31nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033461((S)-N-((S)-1-Hydroxymethyl-3,3-dimethyl-butyl)-3-(...)
Affinity DataIC50:  34nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033449((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-2-[(S)-3,3-dime...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053987((S)-N-(2,2-Dimethyl-propyl)-3-((S)-2-{(S)-2-[3-(1-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033455((S)-2-((S)-3-Carboxy-2-{(S)-2-[(S)-2-(2-ethyl-buty...)
Affinity DataIC50:  43nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50369049(CHEMBL1790855)
Affinity DataIC50:  61nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3900((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  72nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3893((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  78nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3902((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  85nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3903((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  99nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053970((S)-N-(3,3-Dimethyl-butyl)-3-((S)-2-{(S)-2-[3-(1-e...)
Affinity DataIC50:  100nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3895((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  100nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137963((1R,2S)-1-((3R,5S)-1-((S)-2-((S)-2-acetamido-2-cyc...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137959(1-{[(R)-(S)-1-[(S)-2-((S)-2-Acetylamino-2-cyclohex...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50175302(CHEMBL3808401)
Affinity DataIC50:  150nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033466((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-(2-Benzyl-3-phen...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50175303(CHEMBL3810042)
Affinity DataIC50:  180nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50033476((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[(S)...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibitory activity against HSV ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3908((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  340nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50053985((S)-3-((S)-2-{(S)-2-[3-(1-Ethyl-propyl)-ureido]-3,...)
Affinity DataIC50:  350nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137965(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50093011(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50093011(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3897((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  420nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3901((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  430nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Bio-M£Ga/Boehringer Ingelheim Research

Curated by ChEMBL
LigandPNGBDBM50050829((S)-2-((S)-3-Carboxy-2-{(S)-2-[(S)-2-(3-isopropyl-...)
Affinity DataIC50:  440nMAssay Description:Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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