Compile Data Set for Download or QSAR
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Found 476 with Last Name = 'müller' and Initial = 'k'
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00400nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50225252(CHEMBL296525)
Affinity DataKi: <0.0100nMAssay Description:Inhibition constant of compound against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027975(5-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.200nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037991(CHEMBL325166 | NAPSAGATRAN | Ro-46-6240 | {[(S)-3-...)
Affinity DataKi:  0.270nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027973(6-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027972(7-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.600nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037976(CHEMBL341260 | {Benzyl-[(S)-3-[((S)-1-carbamimidoy...)
Affinity DataKi:  0.680nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037995(CHEMBL338669 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  0.710nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037984(CHEMBL339094 | {Butyl-[(S)-3-[((S)-1-carbamimidoyl...)
Affinity DataKi:  0.860nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027971(4-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027977(2-{3-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)...)
Affinity DataKi:  1.70nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037983((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219137(7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027976(CHEMBL45202 | {3-[2-Bromo-5-(2,4-diamino-pyrimidin...)
Affinity DataKi:  4.10nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50378584(STEPHOLIDINE)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50219142(3-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibe...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037997((S)-4-Azocan-1-yl-N-(1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  4.80nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027974(3-{3-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)...)
Affinity DataKi:  5.30nMAssay Description:Inhibition constant of compound against L. casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50378584(STEPHOLIDINE)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037994((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  6.70nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037992((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50219137(7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027970(5-(4-Bromo-3,5-dimethoxy-benzyl)-pyrimidine-2,4-di...)
Affinity DataKi:  11nMAssay Description:Inhibition constant of compound against L. casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]spiperone from rat dopamine D4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037978(CHEMBL543893 | {[(S)-3-[((S)-1-Carbamimidoyl-piper...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50184429(16-methoxy-11-methyl-11-aza-tricyclo[12.4.0.03,8]o...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219138(7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...)
Affinity DataKi:  13.9nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(RAT)
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]SCH23390 from rat dopamine D5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50219138(7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]az...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50180913(11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...)
Affinity DataKi:  17.5nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037987((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219142(3-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibe...)
Affinity DataKi:  18.5nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037993((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-4-mor...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219148(3-methoxy-8-methyl-5,6,7,8,9,10,11,16-octahydrodib...)
Affinity DataKi:  23.5nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219140(12-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dib...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50184429(16-methoxy-11-methyl-11-aza-tricyclo[12.4.0.03,8]o...)
Affinity DataKi:  28.5nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50219140(12-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dib...)
Affinity DataKi:  29.4nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50378584(STEPHOLIDINE)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  31nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  35.7nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037982((R)-3-(4-Acetylamino-phenyl)-N-(1-carbamimidoyl-pi...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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