Affinity DataKi: 1.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Mixed type inhibition of electric eel AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate addition and measured after 15 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Mixed-type inhibition of electric eel AChE preincubated for 5 mins followed by varying levels acetylthiocholine iodide substrate addition by Lineweav...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Mixed-type inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 209nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measur...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataKi: 3.19E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate measured for 2 mins by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity was determined against bovine liver beta galactosidaseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 6 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus-infected insect cells using Rh-EVNLDAEFK-quencher as substrate mea...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 using Rh-EVNLDAEFK-quencher as substrate measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus-infected insect cells using Rh-EVNLDAEFK-quencher as substrate mea...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 1 min by E...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using Rh-EVNLDAEFK-Quencher as substrate inc...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:The stock solutions of the target compounds were prepared in a mixture of DMSO (1 ml) and ethanol (9 ml) and diluted with 0.1 MKH2PO4/K2HPO4 buffer (...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Zanjan
Curated by ChEMBL
University Of Zanjan
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair