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Found 36 with Last Name = 'malla' and Initial = 'rk'
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064422(CHEMBL3401162)
Affinity DataKi:  40nMAssay Description:Irreversible inhibition of rat hormone sensitive lipase assessed as relative residual activity by kinetic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50022772(CHEMBL1025 | Diisopropoxyphosphoryl fluoride | Dii...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308513((3R,8aR)-3-Methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308513((3R,8aR)-3-Methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308517(2-Methoxy-6-methyl-2-oxo-3,4-dihydro-2H-2lambda*5*...)
Affinity DataKi:  3.10E+5nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064422(CHEMBL3401162)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064413(CHEMBL3401168)
Affinity DataIC50:  60nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064423(CHEMBL3401161)
Affinity DataIC50:  75nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50022772(CHEMBL1025 | Diisopropoxyphosphoryl fluoride | Dii...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064414(CHEMBL3401167)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064421(CHEMBL3401163)
Affinity DataIC50:  420nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064418(CHEMBL3401164)
Affinity DataIC50:  450nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064416(CHEMBL3401165)
Affinity DataIC50:  470nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064425(CHEMBL3401160)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308513((3R,8aR)-3-Methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308517(2-Methoxy-6-methyl-2-oxo-3,4-dihydro-2H-2lambda*5*...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308514((2R,6R)-6-Benzyloxymethyl-2-methoxy-4-methyl-2-oxo...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064415(CHEMBL3401166)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308515(2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lambd...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064408(CHEMBL3401171)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064410(CHEMBL3401170)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064427(CHEMBL3401172)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308513((3R,8aR)-3-Methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308514((2R,6R)-6-Benzyloxymethyl-2-methoxy-4-methyl-2-oxo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064411(CHEMBL2179369)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064409(CHEMBL2179367)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308519((E)-Dimethyl 1-(2-oxodihydrofuran-3(2H)-ylidene)et...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308513((3R,8aR)-3-Methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064426(CHEMBL3401159)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064428(CHEMBL2179365)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50064412(CHEMBL3401169)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308516((2-Methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-2lamb...)
Affinity DataIC50:  6.00E+5nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308518((Z)-Dimethyl 1-(2-oxodihydrofuran-3(2H)-ylidene)et...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed