Affinity DataIC50: 0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Irreversible inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in pre...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of CYP3A4 (unknown origin) using AMMC by fluorescence assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol after 24 hrs by thin layer ch...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate by scintillation counting methodMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Concentration to inhibit 50% activity of the Type-3 17-beta- hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in pre...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 2More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 1More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Concentration to inhibit 50% activity of the Type-3 17-beta- hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol after 24 hrs by thin layer ch...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Reversible inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Concentration to inhibit 50% activity of the Type-3 17-beta- hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Concentration to inhibit 50% activity of the Type-3 17-beta- hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Concentration to inhibit 50% activity of the Type-3 17-beta- hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in human LNCAP cells assessed as conversion of [14C]-4-androstene-3,17-dione into [14C]-testost...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 3More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta-HSD3 (unknown origin) expressed in human LNCaP cells using [14C]-4-androstene-3,17-dione as substrate assessed as reduction of ...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CYP2D6 (unknown origin) using AMMC by fluorescence assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 17-beta-HSD3 (unknown origin) expressed in human LNCaP cells using [14C]-4-androstene-3,17-dione as substrate assessed as reduction of ...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Chu De Qu£Bec-Research Center (Chul)
Curated by ChEMBL
Affinity DataIC50: 169nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Chu De Qu£Bec-Research Center
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair