Affinity DataKi: 5.90nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against hMC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against hMC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]NDPalphaMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against hMC5R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against hMC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair