Affinity DataIC50: 7.90nMAssay Description:Inhibition of mouse FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of rat FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human CaV1.2 channel expressed in HEK293 cells by FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as intracellular calcium level by fluorescence/summary (Abse5) as...More data for this Ligand-Target Pair
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as intracellular calcium level by fluorescence/summary (Abse5) as...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human PI3K gamma by TR-FRET/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARgamma by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARgamma by SPA/Abse5 assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARdelta by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARdelta by SPA/Abse5 assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2.51E+4nMAssay Description:Antagonist activity at human ACVR2B by Ant A204 luciferase reporter/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human GSK3B by FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2.51E+4nMAssay Description:Antagonist activity at human MC4 receptor assessed as cAMP level by HTRF LANCE/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human PDE4B by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human FFA1 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARalpha by SPA/Abse5 assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARalpha by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.02E+4nMAssay Description:Antagonist activity at human dopamine D2 receptor by GTPgS SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human 5-HT1B receptor by LEADseeker GTPgS/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human GPR41 expressed in U2OS cells by brilliant black FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human dopamine D2 receptor by GTPgS SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human beta 2 adrenergic receptor by TR FRET/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human 5-HT2A receptor expressed in HEK cells by luminescence/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <3.98E+4nMAssay Description:Blocking of human TRPC3 expressed in HEK cells by MSRII FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human TAS2R16 expressed in U2OS cells by Ga16gust44 Clone 7A FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human TAS2R14 expressed in U2OS cells by Ga16gust44 Clone 7A FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetSolute carrier family 5 (neutral amino acid transporters, system A), member 4b(Mus musculus)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <3.98E+4nMAssay Description:Inhibition of mouse SGLT3b expressed in U2OS cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Inhibition of human SGLT1 expressed in U2OS cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human PePT1 receptor expressed in HEK cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human histamine H1 receptor by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human GPR43 expressed in U2OS cells by BacMam FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human adrenergic alpha1B receptor assessed as intracellular calcium by summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human 5-HT2C receptor expressed in CHO cells by luminescence/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <3.98E+4nMAssay Description:Blocking of human TRPM5 expressed in HEK293 cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human vasopressin V1a receptor by double wash FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human GIP receptor expressed in HEK293 cells by IP4 HTRF EFC cAMP/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human glucagon receptor expressed in CHO-K1 cells by LANCE HTRF/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by dofetilide binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human NK1 receptor by FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human DAT by BacMam Binding SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by electrophysiologyMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human NET by BacMam bind SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human OPRK1 receptor by BacMam GTPgS LEADseeker/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human OPRM1 receptor by BacMam GTPgS LEADseeker/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human COX2 by FLINT/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human SERT by BacMam binding SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPRMore data for this Ligand-Target Pair