Compile Data Set for Download or QSAR
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Found 140 with Last Name = 'mccoy' and Initial = 'dc'
TargetFree fatty acid receptor 4(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044874(CHEMBL3311302)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of mouse FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044874(CHEMBL3311302)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of rat FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044874(CHEMBL3311302)
Affinity DataIC50:  79nMAssay Description:Inhibition of human FFA4 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human CaV1.2 channel expressed in HEK293 cells by FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as intracellular calcium level by fluorescence/summary (Abse5) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.58E+4nMAssay Description:Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as intracellular calcium level by fluorescence/summary (Abse5) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human PI3K gamma by TR-FRET/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARgamma by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARgamma by SPA/Abse5 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARdelta by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARdelta by SPA/Abse5 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Antagonist activity at human ACVR2B by Ant A204 luciferase reporter/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human GSK3B by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Antagonist activity at human MC4 receptor assessed as cAMP level by HTRF LANCE/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human PDE4B by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044874(CHEMBL3311302)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of human FFA1 receptor expressed in U2OS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARalpha by SPA/Abse5 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <2.51E+4nMAssay Description:Binding affinity to human PPARalpha by SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.02E+4nMAssay Description:Antagonist activity at human dopamine D2 receptor by GTPgS SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human 5-HT1B receptor by LEADseeker GTPgS/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human GPR41 expressed in U2OS cells by brilliant black FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human dopamine D2 receptor by GTPgS SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.16E+4nMAssay Description:Antagonist activity at human beta 2 adrenergic receptor by TR FRET/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human 5-HT2A receptor expressed in HEK cells by luminescence/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Blocking of human TRPC3 expressed in HEK cells by MSRII FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 16(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human TAS2R16 expressed in U2OS cells by Ga16gust44 Clone 7A FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human TAS2R14 expressed in U2OS cells by Ga16gust44 Clone 7A FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Inhibition of mouse SGLT3b expressed in U2OS cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Inhibition of human SGLT1 expressed in U2OS cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human PePT1 receptor expressed in HEK cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human histamine H1 receptor by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human GPR43 expressed in U2OS cells by BacMam FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human adrenergic alpha1B receptor assessed as intracellular calcium by summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Antagonist activity at human 5-HT2C receptor expressed in CHO cells by luminescence/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <3.98E+4nMAssay Description:Blocking of human TRPM5 expressed in HEK293 cells by FLIPR membrane potential/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human vasopressin V1a receptor by double wash FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human GIP receptor expressed in HEK293 cells by IP4 HTRF EFC cAMP/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human glucagon receptor expressed in CHO-K1 cells by LANCE HTRF/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by dofetilide binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Antagonist activity at human NK1 receptor by FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human DAT by BacMam Binding SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human NET by BacMam bind SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human OPRK1 receptor by BacMam GTPgS LEADseeker/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human OPRM1 receptor by BacMam GTPgS LEADseeker/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human COX2 by FLINT/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human SERT by BacMam binding SPA/summary (Abse5) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044846(CHEMBL3311324)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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