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Found 16 with Last Name = 'melck' and Initial = 'd'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.530nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM20462((5Z,8Z,11Z,14Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]ic...)
Affinity DataKi:  380nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM50096883((5Z,8Z,11Z,14Z,17Z)-Icosa-5,8,11,14,17-pentaenoic ...)
Affinity DataKi:  620nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089073(({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  720nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Affinity DataKi:  800nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM50096881((10Z,13Z,16Z,19Z)-Docosa-7,10,13,16,19-pentaenoic ...)
Affinity DataKi:  1.37E+3nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089075(2-({1-[2-({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  1.44E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089071(({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  1.62E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM50096882((5Z,9Z,12Z)-Octadeca-5,9,12-trienoic acid [2-(3,4-...)
Affinity DataKi:  1.72E+3nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM50096885((6Z,9Z,12Z,15Z)-Octadeca-6,9,12,15-tetraenoic acid...)
Affinity DataKi:  2.43E+3nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Institute Of Bioorganic Chemistry Ras

Curated by ChEMBL
LigandPNGBDBM50096884((9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid [2-(3,...)
Affinity DataKi:  3.13E+3nMAssay Description:Concentration required to displace 0.4 nM [3H]-SR-141,716A from CB1 receptor in rat brain preparations in the presence of 0.1 mM phenylmethyl sulphon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089072(2-({1-[2-({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  7.54E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089073(({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089075(2-({1-[2-({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089071(({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089072(2-({1-[2-({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed