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Found 222 with Last Name = 'menard' and Initial = 'r'
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50079881(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[1-(1-imi...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50079882(1-[(R)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydro-...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi:  5.30E+3nM ΔG°:  -29.9kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86096(2-Cyanopyrrolidine Derivative, 25)
Affinity DataKi:  8.60E+3nM ΔG°:  -28.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86094(2-Cyanopyrrolidine Derivative, 23)
Affinity DataKi:  6.70E+4nM ΔG°:  -23.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi:  7.50E+4nM ΔG°:  -23.4kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86093(2-Cyanopyrrolidine Derivative, 22)
Affinity DataKi:  8.50E+4nM ΔG°:  -23.1kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86094(2-Cyanopyrrolidine Derivative, 23)
Affinity DataKi:  9.20E+4nM ΔG°:  -22.9kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86097(2-Cyanopyrrolidine Derivative, 26)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86098(2-Cyanopyrrolidine Derivative, 27)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86100(2-Cyanopyrrolidine Derivative, 29)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86100(2-Cyanopyrrolidine Derivative, 29)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86098(2-Cyanopyrrolidine Derivative, 27)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86097(2-Cyanopyrrolidine Derivative, 26)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86096(2-Cyanopyrrolidine Derivative, 25)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86093(2-Cyanopyrrolidine Derivative, 22)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86099(2-Cyanopyrrolidine Derivative, 28)
Affinity DataKi: >1.00E+5nM ΔG°: >-22.7kJ/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  0nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020833(CHEMBL326137 | [(3-Chloro-2-mercapto-benzoyl)-cycl...)
Affinity DataIC50:  0nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020840(CHEMBL113276 | [Cyclopentyl-(2-mercapto-3-methoxy-...)
Affinity DataIC50:  0nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020829(CHEMBL114242 | [(2-Acetylsulfanyl-3-fluoro-benzoyl...)
Affinity DataIC50:  0.00100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020830(CHEMBL263056 | [Cyclopentyl-(2-mercapto-3-trifluor...)
Affinity DataIC50:  0.00100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020824(CHEMBL325659 | [Cyclopentyl-(3-fluoro-2-mercapto-b...)
Affinity DataIC50:  0.00100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020831(CHEMBL113315 | [(2-Acetylsulfanyl-3-methyl-benzoyl...)
Affinity DataIC50:  0.00200nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020842(CHEMBL114294 | [Cyclopentyl-(3,5-dichloro-2-mercap...)
Affinity DataIC50:  0.00400nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020841(CHEMBL324242 | [Cyclopentyl-(2-mercapto-3-methyl-b...)
Affinity DataIC50:  0.00500nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020825(CHEMBL112168 | [Cyclopentyl-(2-mercapto-benzoyl)-a...)
Affinity DataIC50:  0.00500nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020823(CHEMBL112477 | [(2-Acetylsulfanyl-benzoyl)-cyclope...)
Affinity DataIC50:  0.00900nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020821(CHEMBL113612 | [Cyclopentyl-(4-mercapto-benzoyl)-a...)
Affinity DataIC50:  0.0210nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020832(CHEMBL112589 | [(4-Acetylsulfanyl-benzoyl)-cyclope...)
Affinity DataIC50:  0.0210nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020827(CHEMBL324898 | [Cyclopentyl-(3-mercapto-benzoyl)-a...)
Affinity DataIC50:  0.0250nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020838(CHEMBL323879 | [(3-Acetylsulfanyl-benzoyl)-cyclope...)
Affinity DataIC50:  0.0280nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020820(CHEMBL112922 | [(5-Chloro-2-mercapto-benzoyl)-cycl...)
Affinity DataIC50:  0.0800nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020837(CHEMBL114018 | [(2-Acetoxy-3,5-dichloro-benzoyl)-c...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020836(CHEMBL115153 | N-Carboxymethyl-N-cyclopentyl-phtha...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121904(CHEMBL30401 | [(S)-1-((3S,4R)-2-Oxo-4-phenoxy-azet...)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020839(CHEMBL324703 | [Cyclopentyl-(2-nitro-benzoyl)-amin...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121907(CHEMBL31788 | [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfan...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121902(CHEMBL287630 | [(S)-1-((2S,3R)-2-Benzenesulfonyl-4...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020828(CHEMBL324676 | [Cyclopentyl-(3,5-dichloro-2-hydrox...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020834(CHEMBL325305 | [Cyclopentyl-(3-isopropyl-2-mercapt...)
Affinity DataIC50:  0.120nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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