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Found 145 with Last Name = 'merlini' and Initial = 'l'
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426684(CHEMBL2326494)
Affinity DataKi:  10nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426683(CHEMBL2326500)
Affinity DataKi:  13nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426683(CHEMBL2326500)
Affinity DataKi:  26nMAssay Description:Inhibition of human FAAH using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after 15 mins by beta coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426688(CHEMBL2326499)
Affinity DataKi:  240nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426692(CHEMBL2326495)
Affinity DataKi:  263nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426693(CHEMBL2326493)
Affinity DataKi:  270nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426686(CHEMBL2326502)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426689(CHEMBL2326498)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426690(CHEMBL2326497)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426691(CHEMBL2326496)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426685(CHEMBL2326503)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426687(CHEMBL2326501)
Affinity DataKi: >500nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]AB-MECA from human recombinant A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]CCK-8 from human recombinant CCKA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323051(1-Biphenyl-3-yl-ethanone, O-(1-naphthylaminocarbon...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323050(1-Biphenyl-3-yl-ethanone, O-(4-fluorophenylaminoca...)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323049(1-Biphenyl-3-yl-ethanone, O-(4-methoxyphenylaminoc...)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426683(CHEMBL2326500)
Affinity DataIC50:  44nMAssay Description:Inhibition of human FAAH using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after 15 mins by beta coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50246572(4-(4-hydroxyphenyl)-2,3-bis(2-methoxyethylidene)-1...)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323052(1-Biphenyl-3-yl-ethanone, O-(phenylaminocarbonyl)o...)
Affinity DataIC50:  69nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50445952(CHEMBL3105886)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323042(1-(3'-Aminocarbonyl-biphenyl-3-yl)-ethanone, O-(ph...)
Affinity DataIC50:  84nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50246605(4-(3-hydroxyphenyl)-6,7-dimethoxy-9-methyl-2H-pyri...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323047(1-Biphenyl-3-yl-ethanone, O-[(4-pentylphenyl)amino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50246571(4-(4-hydroxyphenyl)-6,7-dimethoxy-2H-pyrido[3,4-b]...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323043(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(1-piperidi...)
Affinity DataIC50:  112nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323044(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(dodecylami...)
Affinity DataIC50:  116nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323057(1-(4-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323046(1-Biphenyl-3-yl-ethanone, O-(1-piperidinocarbonyl)...)
Affinity DataIC50:  220nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50445970(CHEMBL3105890)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293352(CHEMBL551486 | N-Hydroxy-E-3-[4'-hydroxymethylbiph...)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323048(1-Biphenyl-3-yl-ethanone, O-[(5-benzo[b]thiophenyl...)
Affinity DataIC50:  232nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50246604(6,7-dimethoxy-9-methyl-4-phenyl-2H-pyrido[3,4-b]in...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50445969(CHEMBL3105876)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50445968(CHEMBL3105879)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50445967(CHEMBL3105888)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293353(CHEMBL539156 | N-Hydroxy-E-3-[4-(4-hydroxyphenyl)-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293354(CHEMBL555906 | N-hydroxy-E-3-[4'-Hydroxybiphenyl-3...)
Affinity DataIC50:  320nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293355(CHEMBL538710 | N-Hydroxy-E-3-(4'-cyanobiphenyl-4-y...)
Affinity DataIC50:  330nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50323058(1-Biphenyl-4-yl-ethanone, O-(1-naphthylaminocarbon...)
Affinity DataIC50:  401nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293356(CHEMBL561212 | N-Hydroxy-E-3-(4'-thiophen-2-yl-phe...)
Affinity DataIC50:  450nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293357(CHEMBL565140 | N-Hydroxy-E-3-[3'-chloro-4'-hydroxy...)
Affinity DataIC50:  460nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita Di Milano

Curated by ChEMBL
LigandPNGBDBM50246573(4-(4-hydroxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol...)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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