Affinity DataKi: 326nMAssay Description:Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Induction of internalization of HA-tagged human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 3.23E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair