Compile Data Set for Download or QSAR
maximum 50k data
Found 224 with Last Name = 'moser' and Initial = 'h'
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153088(CHEMBL365416 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  0.220nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153085(CHEMBL364836 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153083(CHEMBL441502 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  0.330nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25771(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153086(CHEMBL188671 | N-[(1R,2S)-3-(4-Amino-butyl)-2,5-di...)
Affinity DataKi:  3nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318156(CHEMBL1094785 | carmoterol)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataKi:  11nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153084(CHEMBL361449 | N-(4-{(3R,14S)-14-[(Formyl-hydroxy-...)
Affinity DataKi:  12nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153087(CHEMBL188894 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  13.7nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50151720(ARFORMOTEROL TARTRATE | CHEMBL1363 | CHEMBL605993 ...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153080((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataKi:  23nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153081(CHEMBL365910 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  25nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153079(CHEMBL364979 | N-[(3S,6R)-3-(4-Amino-butyl)-2,5-di...)
Affinity DataKi:  36nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by AAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153087(CHEMBL188894 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  63nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153082((R)-2-[(Formyl-hydroxy-amino)-methyl]-heptanoic ac...)
Affinity DataKi:  74nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataKi:  76nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153088(CHEMBL365416 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  77nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153086(CHEMBL188671 | N-[(1R,2S)-3-(4-Amino-butyl)-2,5-di...)
Affinity DataKi:  92nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153085(CHEMBL364836 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  96nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153083(CHEMBL441502 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  109nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318157(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-di-n-butylindan-...)
Affinity DataKi:  112nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318158(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-di-n-propylindan...)
Affinity DataKi:  119nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318161(8-Hydroxy-5-[(R)-1-hydroxy-2-(indan-2-ylamino)-eth...)
Affinity DataKi:  218nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153079(CHEMBL364979 | N-[(3S,6R)-3-(4-Amino-butyl)-2,5-di...)
Affinity DataKi:  258nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318155(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-dimethoxyindan-2...)
Affinity DataKi:  342nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318160(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-dimethylindan-2-...)
Affinity DataKi:  522nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318154(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
Affinity DataKi:  692nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153084(CHEMBL361449 | N-(4-{(3R,14S)-14-[(Formyl-hydroxy-...)
Affinity DataKi:  710nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25769(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Affinity DataKi:  1.83E+3nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50153081(CHEMBL365910 | N-((3S,6R)-3-tert-Butyl-2,5-dioxo-1...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207120(3-isobutyl-8-((6-methoxyisoquinolin-4-yl)methyl)-1...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318153((2S,3S,4S,5R,6S)-6-(5-((R)-2-(5,6-diethyl-2,3-dihy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318156(CHEMBL1094785 | carmoterol)
Affinity DataIC50:  0.300nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50151720(ARFORMOTEROL TARTRATE | CHEMBL1363 | CHEMBL605993 ...)
Affinity DataIC50:  0.400nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318161(8-Hydroxy-5-[(R)-1-hydroxy-2-(indan-2-ylamino)-eth...)
Affinity DataIC50:  0.830nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207130(8-((6,7-dimethoxy-1-methylisoquinolin-4-yl)methyl)...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207120(3-isobutyl-8-((6-methoxyisoquinolin-4-yl)methyl)-1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318155(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-dimethoxyindan-2...)
Affinity DataIC50:  2.30nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50117734(8-{5-[4-(2-Hydroxy-ethyl)-piperidine-1-sulfonyl]-2...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117721(3-Isobutyl-1-methyl-8-[5-(piperazin-1-ylmethanesul...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50117711(8-{5-[4-(2-Hydroxy-ethyl)-piperazine-1-sulfonyl]-2...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50117719(4-[3-(3-Isobutyl-1-methyl-2,6-dioxo-2,3,6,7-tetrah...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM25771(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)
Affinity DataIC50:  3.5nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50117724(3-(3-Isobutyl-1-methyl-2,6-dioxo-2,3,6,7-tetrahydr...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207121(CHEMBL245648 | N-(4-((8-((6,7-dimethoxyisoquinolin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50117721(3-Isobutyl-1-methyl-8-[5-(piperazin-1-ylmethanesul...)
Affinity DataIC50:  5.5nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207123(8-((6,7-dimethoxyisoquinolin-4-yl)methyl)-3-(3-hyd...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117715(3-Isobutyl-1-methyl-8-[5-(4-methyl-piperazine-1-su...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataIC50:  7.90nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50207127(8-((6,7-dimethoxyisoquinolin-4-yl)methyl)-1-methyl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 224 total ) | Next | Last >>
Jump to: